High frequency of mutations of the PIK3CA gene in human cancers - Wikidata - awgldk - TriplyDB

High frequency of mutations of the PIK3CA gene in human cancers

High frequency of mutations of the PIK3CA gene in human cancers

http://www.wikidata.org/entity/Q28131776

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Gene expression profiling reveals new aspects of PIK3CA mutation in ERalpha-positive breast cancer: major implication of the Wnt signaling pathway Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation Main roads to melanoma Mutations of PIK3CA in gastric adenocarcinoma Mutational profiling of kinases in glioblastoma.PI-3 kinase activity is necessary for ERK1/2-induced disruption of mammary epithelial architecture.Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review Akt phosphorylates and suppresses the transactivation of retinoic acid receptor alpha Second AKT: the rise of SGK in cancer signalling Should individual PI3 kinase isoforms be targeted in cancer?Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets Gain of interaction with IRS1 by p110α-helical domain mutants is crucial for their oncogenic functions Markers of resistance to anti-EGFR therapy in colorectal cancer A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling Analysis of the genome to personalize therapy for melanoma Protein kinases and phosphatases in the control of cell fate Somatic mosaic activating mutations in PIK3CA cause CLOVES syndrome Molecular biology of lung cancer: clinical implications Retroviral oncogenes: a historical primer International network of cancer genome projects.Molecular origins of cancer: Molecular basis of colorectal cancer Pushing the envelope in the mTOR pathway: the second generation of inhibitors De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes Loss of PHLPP expression in colon cancer: role in proliferation and tumorigenesis The PI3K pathway as drug target in human cancer Mosaic overgrowth with fibroadipose hyperplasia is caused by somatic activating mutations in PIK3CA Emerging common themes in regulation of PIKKs and PI3Ks Potential therapeutic targets for chordoma: PI3K/AKT/TSC1/TSC2/mTOR pathway An integrated genomic analysis of human glioblastoma multiforme Tumours with PI3K activation are resistant to dietary restriction Whole-genome cancer analysis as an approach to deeper understanding of tumour biology Comprehensive genomic characterization defines human glioblastoma genes and core pathways Brick by brick: metabolism and tumor cell growth Knockin of mutant PIK3CA activates multiple oncogenic pathways The noncoding RNA, miR-126, suppresses the growth of neoplastic cells by targeting phosphatidylinositol 3-kinase signaling and is frequently lost in colon cancers New molecularly targeted therapies for lung cancer Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon Mucinous differentiation correlates with absence of EGFR mutation and presence of KRAS mutation in lung adenocarcinomas with bronchioloalveolar features New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists A simplified immunoprecipitation method for quantitatively measuring antibody responses in clinical sera samples by using mammalian-produced Renilla luciferase-antigen fusion proteins

P2860

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P2860

High frequency of mutations of the PIK3CA gene in human cancers

http://www.wikidata.org/entity/Q28131776

description

2004 nî lūn-bûn

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2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2004 թվականի ապրիլին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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name

High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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High frequency of mutations of the PIK3CA gene in human cancers

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Adi Gazdar

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Gregory J Riggins

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Hai Yan

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James K V Willson

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Janine Ptak

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Steven M Powell

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Zhenghe Wang

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Kenneth W Kinzler

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