The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome
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Members of the Jagged/Notch gene families are expressed in injured arteries and regulate cell phenotype via alterations in cell matrix and cell-cell interactionNotch signaling is essential for ventricular chamber developmentJagged1 (JAG1) mutations in patients with tetralogy of Fallot or pulmonic stenosisSlug is a direct Notch target required for initiation of cardiac cushion cellularizationJAGGED1 expression in human embryos: correlation with the Alagille syndrome phenotypeCoordinating tissue interactions: Notch signaling in cardiac development and diseaseStability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle developmentEndothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndromeNotch1 signaling stimulates proliferation of immature cardiomyocytesJagged1 (JAG1): Structure, expression, and disease associationsDiscovery of novel determinants of endothelial lineage using chimeric heterokaryons.Activation of Notch signaling by short-term treatment with Jagged-1 enhances store-operated Ca(2+) entry in human pulmonary arterial smooth muscle cellsGene expression in pediatric heart disease with emphasis on conotruncal defects.Embryonic Development of the Bicuspid Aortic Valve.Jagged1 mutations in alagille syndrome.Facial features in Alagille syndrome: specific or cholestasis facies?Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion.Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defectsLoss of Gata5 in mice leads to bicuspid aortic valve.Gene Transcriptional and Metabolic Profile Changes in Mimetic Aging Mice Induced by D-GalactoseThe role of notch in modeling and maintaining the vasculature.Cartilage, SOX9 and Notch signals in chondrogenesis.Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation.Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box proteinFamilial deafness, congenital heart defects, and posterior embryotoxon caused by cysteine substitution in the first epidermal-growth-factor-like domain of jagged 1.Notch signaling in cardiac valve development and disease.Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development.Developmental and extracellular matrix-remodeling processes in rosiglitazone-exposed neonatal rat cardiomyocytes.A Serrate-expressing signaling center controls Drosophila hematopoiesis.Jagged1-selective notch signaling induces smooth muscle differentiation via a RBP-Jkappa-dependent pathway.Ectopic Noggin in a Population of Nfatc1 Lineage Endocardial Progenitors Induces Embryonic Lethality.Notch1 and Jagged1 expression by the developing pulmonary vasculature.A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse.Aortic coarctation and carotid artery aneurysm in a patient with Hardikar syndrome: Cardiovascular implications for affected individuals.JAG1Mutation in a patient with deletion 22q11.2 syndrome and tetralogy of Fallot
P2860
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P2860
The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome
description
1999 nî lūn-bûn
@nan
1999 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@ast
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@en
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@nl
type
label
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@ast
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@en
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@nl
prefLabel
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@ast
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@en
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@nl
P2093
P2860
P356
P1476
The expression of Jagged1 in t ...... r disease in Alagille syndrome
@en
P2093
D A Piccoli
H S Baldwin
J Morabito
K M Loomes
L A Underkoffler
N B Spinner
S Gottlieb
P2860
P304
P356
10.1093/HMG/8.13.2443
P407
P577
1999-12-01T00:00:00Z