Gli proteins encode context-dependent positive and negative functions: implications for development and disease
about
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and functionRepression of smoothened by patched-dependent (pro-)vitamin D3 secretionThe sonic hedgehog-patched-gli pathway in human development and diseaseMediator modulates Gli3-dependent Sonic hedgehog signalingSki is involved in transcriptional regulation by the repressor and full-length forms of Gli3Inhibition of GLI1 gene activation by Patched1Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentGli proteins and the control of spinal-cord patterningRegulatory role for Krüppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis.GLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cellsGli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activationThe therapeutic potential of modulators of the Hedgehog-Gli signaling pathwayKrüppel-like zinc finger protein Gli-similar 2 (Glis2) represses transcription through interaction with C-terminal binding protein 1 (CtBP1).Cooperative integration between HEDGEHOG-GLI signalling and other oncogenic pathways: implications for cancer therapyWrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsContext-dependent signal integration by the GLI code: the oncogenic load, pathways, modifiers and implications for cancer therapyEvolutionary change within a bipotential switch shaped the sperm/oocyte decision in hermaphroditic nematodesPhosphorylation regulates OLIG2 cofactor choice and the motor neuron-oligodendrocyte fate switchHepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levelsHippi is essential for node cilia assembly and Sonic hedgehog signalingSonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradationThe primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationThe transcription factor Gli3 regulates differentiation of fetal CD4- CD8- double-negative thymocytes.Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tubeGli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiationGLIS3, a novel member of the GLIS subfamily of Krüppel-like zinc finger proteins with repressor and activation functionsHigh frequency of cephalic neural crest cells shows coexistence of neurogenic, melanogenic, and osteogenic differentiation capacitiesThe expression of Gli3, regulated by HOXD13, may play a role in idiopathic congenital talipes equinovarusInsights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling.LMP4 regulates Tbx5 protein subcellular localization and activity.Turning heads: development of vertebrate branchiomotor neurons.Autocrine Sonic hedgehog attenuates inflammation in cerulein-induced acute pancreatitis in mice via upregulation of IL-10.Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells.Estrogen promotes stemness and invasiveness of ER-positive breast cancer cells through Gli1 activation.Visualization of Gli activity in craniofacial tissues of hedgehog-pathway reporter transgenic zebrafish.Ketamine induces motor neuron toxicity and alters neurogenic and proneural gene expression in zebrafish.Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling.Human GLI-2 is a tat activation response element-independent Tat cofactor.
P2860
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P2860
Gli proteins encode context-dependent positive and negative functions: implications for development and disease
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Gli proteins encode context-de ...... ns for development and disease
@ast
Gli proteins encode context-de ...... ns for development and disease
@en
Gli proteins encode context-de ...... ns for development and disease
@nl
type
label
Gli proteins encode context-de ...... ns for development and disease
@ast
Gli proteins encode context-de ...... ns for development and disease
@en
Gli proteins encode context-de ...... ns for development and disease
@nl
prefLabel
Gli proteins encode context-de ...... ns for development and disease
@ast
Gli proteins encode context-de ...... ns for development and disease
@en
Gli proteins encode context-de ...... ns for development and disease
@nl
P3181
P1433
P1476
Gli proteins encode context-de ...... ns for development and disease
@en
P2093
A Ruiz i Altaba
P304
P3181
P407
P577
1999-06-01T00:00:00Z