Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells
about
Structural and functional alterations of FLT3 in acute myeloid leukemiaClass III Receptor Tyrosine Kinases in Acute Leukemia - Biological Functions and Modern Laboratory AnalysisAn overview on the role of FLT3-tyrosine kinase receptor in acute myeloid leukemia: biology and treatmentSurvey of activated FLT3 signaling in leukemiaKnock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse modelPhosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion.Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).Tyrosine kinase inhibitors targeting FLT3 in the treatment of acute myeloid leukemia.The Cytokine Flt3-Ligand in Normal and Malignant HematopoiesisInhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease.The Biology and Targeting of FLT3 in Pediatric Leukemia.Incorporating FLT3 inhibitors into acute myeloid leukemia treatment regimens.Functional pathway analysis using SCNP of FLT3 receptor pathway deregulation in AML provides prognostic information independent from mutational statusGene mutations and molecularly targeted therapies in acute myeloid leukemia.FLT3/ITD AML and the law of unintended consequences.Further activation of FLT3 mutants by FLT3 ligandClinical Response to Sorafenib in a Patient with Metastatic Colorectal Cancer and FLT3 AmplificationThe expression of adipogenic genes is decreased in obesity and diabetes mellitusInositol phospholipid signaling and the biology of natural killer cells.Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling.Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation.A role for SHIP in stem cell biology and transplantation.The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.Bench to bedside targeting of FLT3 in acute leukemia.Inhibitor and activator: dual functions for SHIP in immunity and cancer.Quizartinib for the treatment of FLT3/ITD acute myeloid leukemia.Profile of pacritinib and its potential in the treatment of hematologic disorders.Molecular control of PtdIns(3,4,5)P3 signaling in neutrophils.Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways.A Flt3- and Ras-dependent pathway primes B cell development by inducing a state of IL-7 responsiveness.Selective Expression of Flt3 within the Mouse Hematopoietic Stem Cell Compartment.SHIP deficiency enhances HSC proliferation and survival but compromises homing and repopulation.Computer simulations of the signalling network in FLT3 +-acute myeloid leukaemia - indications for an optimal dosage of inhibitors against FLT3 and CDK6.
P2860
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P2860
Flt3 signaling involves tyrosyl-phosphorylation of SHP-2 and SHIP and their association with Grb2 and Shc in Baf3/Flt3 cells
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@ast
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@en
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@nl
type
label
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@ast
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@en
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@nl
prefLabel
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@ast
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@en
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@nl
P2093
P1476
Flt3 signaling involves tyrosy ...... rb2 and Shc in Baf3/Flt3 cells
@en
P2093
P304
P407
P577
1999-03-01T00:00:00Z