about
Molecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted TherapyNext generation MUT-MAP, a high-sensitivity high-throughput microfluidics chip-based mutation analysis panelRelapsed acute myeloid leukemia: why is there no standard of care?The Biology and Targeting of FLT3 in Pediatric Leukemia.BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.FLT3/ITD AML and the law of unintended consequences.Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven LeukemogenesisFluvastatin inhibits FLT3 glycosylation in human and murine cells and prolongs survival of mice with FLT3/ITD leukemia.Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses.Effect of FLT3 ligand on survival and disease phenotype in murine models harboring a FLT3 internal tandem duplication mutation.Recent advances and novel agents for FLT3 mutated acute myeloid leukemia.How I treat FLT3-mutated AML.TTT-3002 is a novel FLT3 tyrosine kinase inhibitor with activity against FLT3-associated leukemias in vitro and in vivo.DOCK2 interacts with FLT3 and modulates the survival of FLT3-expressing leukemia cells.NT1721, a novel epidithiodiketopiperazine, exhibits potent in vitro and in vivo efficacy against acute myeloid leukemia.Targeting the FMS-like tyrosine kinase 3 in acute myeloid leukemia.Quizartinib for the treatment of FLT3/ITD acute myeloid leukemia.Targeting FLT3 to treat leukemia.A novel three-dimensional stromal-based model for in vitro chemotherapy sensitivity testing of leukemia cells.Mechanisms of apoptosis induction by simultaneous inhibition of PI3K and FLT3-ITD in AML cells in the hypoxic bone marrow microenvironment.Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Further activation of FLT3 mutants by FLT3 ligand
@ast
Further activation of FLT3 mutants by FLT3 ligand
@en
type
label
Further activation of FLT3 mutants by FLT3 ligand
@ast
Further activation of FLT3 mutants by FLT3 ligand
@en
prefLabel
Further activation of FLT3 mutants by FLT3 ligand
@ast
Further activation of FLT3 mutants by FLT3 ligand
@en
P2093
P2860
P356
P1433
P1476
Further activation of FLT3 mutants by FLT3 ligand
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2011.110
P407
P577
2011-04-25T00:00:00Z