Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
about
Cereulide synthetase gene cluster from emetic Bacillus cereus: structure and location on a mega virulence plasmid related to Bacillus anthracis toxin plasmid pXO1Patellamide A and C biosynthesis by a microcin-like pathway in Prochloron didemni, the cyanobacterial symbiont of Lissoclinum patellaSelective interaction between nonribosomal peptide synthetases is facilitated by short communication-mediating domains"Splicing up" drug discovery. Cell-based expression and screening of genetically-encoded libraries of backbone-cyclized polypeptidesDiscovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Structure and Catalytic Mechanism of the Thioesterase CalE7 in Enediyne BiosynthesisDifferent active-site loop orientation in serine hydrolases versus acyltransferasesThe mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domainThe high resolution structure of tyrocidine A reveals an amphipathic dimerHeterologous expression and structural characterisation of a pyrazinone natural product assembly lineBiomimetic synthesis and optimization of cyclic peptide antibioticsButelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesisProduction of the catechol type siderophore bacillibactin by the honey bee pathogen Paenibacillus larvaeThe thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides.The biosynthetic gene cluster of zorbamycin, a member of the bleomycin family of antitumor antibiotics, from Streptomyces flavoviridis ATCC 21892.Identification and partial characterization of the nonribosomal peptide synthetase gene responsible for cereulide production in emetic Bacillus cereusDecoding and reprogramming fungal iterative nonribosomal peptide synthetases.Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli.Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.Diversity of nonribosomal peptide synthetases involved in the biosynthesis of lipopeptide biosurfactants.Genetics and assembly line enzymology of siderophore biosynthesis in bacteria.Mapping the limits of substrate specificity of the adenylation domain of TycA.Macrolactonization of peptide thioesters catalyzed by imidazole and its application in the synthesis of kahalalide B and analoguesNonribosomal peptide synthetases involved in the production of medically relevant natural products.Elucidation of sevadicin, a novel non-ribosomal peptide secondary metabolite produced by the honey bee pathogenic bacterium Paenibacillus larvae.Enzyme-catalyzed macrocyclization of long unprotected peptides.Generation of a genetically encoded, photoactivatable intein for the controlled production of cyclic peptides.Learning from nature's drug factories: nonribosomal synthesis of macrocyclic peptides.Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslinkStructural aspects of non-ribosomal peptide biosynthesis.Preparation of Semisynthetic Peptides Macrocycles Using Split Inteins.Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds.Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS-PKS hybrid enzymeNonribosomal Peptide Synthesis-Principles and Prospects.Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptidesCyclization of synthetic seco-proansamitocins to ansamitocin macrolactams by Actinosynnema pretiosum as biocatalystCyanobacterial peptides - nature's own combinatorial biosynthesis.Explorations of catalytic domains in non-ribosomal peptide synthetase enzymologyActivity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometrySubstrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2
P2860
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P2860
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@ast
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@en
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@nl
type
label
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@ast
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@en
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@nl
prefLabel
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@ast
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@en
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@nl
P2093
P3181
P356
P1433
P1476
Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase
@en
P2093
J W Trauger
M A Marahiel
P2888
P3181
P356
10.1038/35025116
P407
P577
2000-09-14T00:00:00Z
P6179
1003337852