Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity - Wikidata - awgldk - TriplyDB

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

http://www.wikidata.org/entity/Q28139967

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Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS APRIL modulates B and T cell immunity B cells, BAFF/zTNF4, TACI, and systemic lupus erythematosus.B-Cell Activating Factor as a Cancer Biomarker and Its Implications in Cancer-Related Cachexia The antigen presenting cells instruct plasma cell differentiation Ligand-receptor binding revealed by the TNF family member TALL-1 Marginal-zone B cells SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription B lymphocyte stimulator (BLyS): a therapeutic trichotomy for the treatment of B lymphocyte diseases DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL B cell-activating factor controls the production of adipokines and induces insulin resistance Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6 APRIL-deficient mice have normal immune system development Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice Aberrant expression of functional BAFF-system receptors by malignant B-cell precursors impacts leukemia cell survival B cell maturation antigen deficiency exacerbates lymphoproliferation and autoimmunity in murine lupus Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI Homeostatic control of B lymphocyte subsets.Transmembrane activator and calcium-modulating cyclophilin ligand interactor mutations in common variable immunodeficiency: clinical and immunologic outcomes in heterozygotes.Neisseria gonorrhoeae kills carcinoembryonic antigen-related cellular adhesion molecule 1 (CD66a)-expressing human B cells and inhibits antibody production.B-cell activating factor-receptor specific activation of tumor necrosis factor receptor associated factor 6 and the phosphatidyl inositol 3-kinase pathway in lymphoma B cells B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses.B-cell homeostasis requires complementary CD22 and BLyS/BR3 survival signals.Genes on chromosomes 1 and 13 have significant effects on Ascaris infection.Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome Microbe-dependent CD11b+ IgA+ plasma cells mediate robust early-phase intestinal IgA responses in mice.Increased B cell-activating factor promotes tumor invasion and metastasis in human pancreatic cancer.Innate control of B cell responses.The C104R mutant impairs the function of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) through haploinsufficiency Transcriptional regulatory cascades controlling plasma cell differentiation.Actions of BAFF in B cell maturation and its effects on the development of autoimmune disease.Molecular mechanisms guiding late stages of B-cell development.The discovery and development of belimumab: the anti-BLyS-lupus connection Dominant-negative effect of the heterozygous C104R TACI mutation in common variable immunodeficiency (CVID)Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sjögren's syndrome TACI-BLyS signaling via B-cell-dendritic cell cooperation is required for naive CD8+ T-cell priming in vivo.The BLyS family of ligands and receptors: an archetype for niche-specific homeostatic regulation.B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease.B cells as a therapeutic target in autoimmune diseases.EBV-encoded latent membrane protein 1 cooperates with BAFF/BLyS and APRIL to induce T cell-independent Ig heavy chain class switching

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P2860

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

http://www.wikidata.org/entity/Q28139967

description

2000 nî lūn-bûn

@nan

2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年論文

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2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

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2000年論文

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2000年论文

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name

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

@ast

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

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Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

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type

label

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

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Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

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Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

@nl

prefLabel

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

@ast

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

@en

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

@nl

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P1433

Nature Immunology

P1476

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

@en

P2093

A Ashkenazi

http://www.w3.org/2001/XMLSchema#string

H Wang

http://www.w3.org/2001/XMLSchema#string

I S Grewal

http://www.w3.org/2001/XMLSchema#string

M Yan

http://www.w3.org/2001/XMLSchema#string

S A Marsters

http://www.w3.org/2001/XMLSchema#string

V M Dixit

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P2860

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR

BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth

LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator

Identification of a ligand for the death-domain-containing receptor Apo3

Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-kappa B

CD28/B7 system of T cell costimulation

NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily

Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

TRANCE is a novel ligand of the tumor necrosis factor receptor family that activates c-Jun N-terminal kinase in T cells

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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37-41

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scholarly article

P3181

1470331

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P356

10.1038/76889

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P407

P433

1

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P478

1

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2000-07-01T00:00:00Z

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P698

10881172

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