Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain
about
The BNIP-2 and Cdc42GAP homology/Sec14p-like domain of BNIP-Salpha is a novel apoptosis-inducing sequenceHuman sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1A novel role of Sprouty 2 in regulating cellular apoptosisTyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its functionDistinct requirements for the Sprouty domain for functional activity of Spred proteinsThe bimodal regulation of epidermal growth factor signaling by human Sprouty proteinsSprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.The cysteine-rich sprouty translocation domain targets mitogen-activated protein kinase inhibitory proteins to phosphatidylinositol 4,5-bisphosphate in plasma membranes.A comprehensive pathway map of epidermal growth factor receptor signalingGrowth factor signaling in lung morphogenetic centers: automaticity, stereotypy and symmetryConcerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1Evidence for direct interaction between Sprouty and CblA functional interaction between sprouty proteins and caveolin-1Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activationThe VASP-Spred-Sprouty domain puzzle.Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loopThe developing story of Sprouty and cancer.Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of Raf.Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway.G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Genomic structure and promoter characterization of the human Sprouty4 gene, a novel regulator of lung morphogenesis.The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization.Sprouty2 downregulates angiogenesis during mouse skin wound healing.Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.Activation of unfolded protein response in transgenic mouse lenses.Identification of a new Sprouty protein responsible for the inhibition of the Bombyx mori nucleopolyhedrovirus reproductionImmunolocalization of sprouty-1 and sprouty-2 in developing rat lungSprouty2 interacts with protein kinase C delta and disrupts phosphorylation of protein kinase D1.Intermolecular interactions of Sprouty proteins and their implications in development and disease.Receptor tyrosine kinase (RTK) signalling in the control of neural stem and progenitor cell (NSPC) development.Sprouty2 Protein Regulates Hypoxia-inducible Factor-α (HIFα) Protein Levels and Transcription of HIFα-responsive Genes.Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A.Downregulation of Spry-1, an inhibitor of GDNF/Ret, causes angiotensin II-induced ureteric bud branching.Sprouty1 inhibits angiogenesis in association with up-regulation of p21 and p27.mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins.The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation.Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling.SPRY2 translocates to the plasma membraneDirect binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation.The C terminus of sprouty is important for modulation of cellular migration and proliferation.
P2860
Q24292005-BD9CC0A8-5FA9-4B11-AA30-9CEE302338AEQ24298028-2B016568-6186-4E2F-A097-7AD9F30CA63BQ24302565-9EA36AA6-6249-4264-B3C6-AD6C3A1F8BDDQ24305529-58CC0D7B-894B-4531-AE01-C9A3852A52ADQ24529002-AF191DEE-E21F-4C41-A51D-CA179EE40B61Q24534190-B7B514E1-A11D-437B-8BC1-52925E6C152AQ24534484-CEEE136B-212E-43B5-B38C-B0FF38E2B83AQ24537706-17BBD735-670A-4D4D-BDE9-690BB1E96271Q24672490-1D68AECB-F463-4913-8C73-8D204AE97B8BQ24795748-922607C3-B89E-4771-9A30-9C43F0EFFAE0Q28114806-F7400457-4E29-4EEE-9D7C-BE4C6A932D9DQ28142352-7743BE29-0004-4337-ACBC-A2C9555BAECAQ28254941-3ECB6832-5C27-4930-933E-9B9F356B862EQ28505657-929E9A53-F621-4325-A3C9-11B923B87B65Q33343173-7ABCF22D-9854-41D7-9BD8-CE4F6AD2F854Q33692471-CB54A420-117A-4A28-9607-ED708725319AQ33962853-4BB3A92B-B9FF-4228-BEBC-DB46521A3837Q34100782-C21EC490-70B0-4912-B886-ABE3141CDC95Q34156402-9A923300-6841-43D6-9623-6D4BB3C2E868Q34181221-0F61902C-233D-40D8-8341-D63CE61425C3Q34300226-9D0E3E35-E328-4B93-B02C-C70567B6B790Q34325524-D3F347A0-946C-4DD3-860D-272F3876F099Q34600328-0CB25A83-94D8-4A38-A9FA-08E4FB406BFCQ34708198-B325B5A3-EC95-4246-9B8E-BA539FBB395CQ34824098-C21B39A5-842F-45F8-BAB5-2539B0764231Q35184880-77F49001-4F7E-4982-9405-6C728F0E65F6Q35726990-FC3BC894-DD59-4ACB-8854-E202366B401FQ37339363-59D777F3-E2AB-47E0-99D0-40E28C602C6DQ37402776-B6A13FCF-07F5-4716-8700-516993075545Q38132066-F3B44564-B5B6-40C8-BD8C-75BE411DA356Q38765470-F30B4F86-85FC-46FD-971E-02ABA92FA672Q39954149-6A688742-E194-415F-81EB-D1AF63CAF6D5Q39957943-B5668BD7-5136-4492-B9E7-A5AE0373363AQ42132860-E0FAA9F6-B1D6-4A12-BFA8-E580362AB0B2Q44133728-DAC17347-E71C-44A4-83E6-10EB3BD3379EQ46863341-15369584-ADC8-4B9B-93A3-00300665CDBEQ48332986-AD61FB44-8F6B-49A5-AF28-79C671B002C0Q50297557-9FCEDB6E-EE4E-4A0C-BD36-23BA26037623Q50336648-F55AD9F8-200C-42E8-83FD-459C4903AF2DQ50336657-CB9DAF56-E5CD-4C8E-83D8-9EC17A76C798
P2860
Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain
description
2000 nî lūn-bûn
@nan
2000 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Sprouty proteins are targeted ...... f a novel translocation domain
@ast
Sprouty proteins are targeted ...... f a novel translocation domain
@en
Sprouty proteins are targeted ...... f a novel translocation domain
@nl
type
label
Sprouty proteins are targeted ...... f a novel translocation domain
@ast
Sprouty proteins are targeted ...... f a novel translocation domain
@en
Sprouty proteins are targeted ...... f a novel translocation domain
@nl
prefLabel
Sprouty proteins are targeted ...... f a novel translocation domain
@ast
Sprouty proteins are targeted ...... f a novel translocation domain
@en
Sprouty proteins are targeted ...... f a novel translocation domain
@nl
P2093
P2860
P356
P1476
Sprouty proteins are targeted ...... f a novel translocation domain
@en
P2093
P2860
P304
P356
10.1074/JBC.M002156200
P407
P577
2000-10-20T00:00:00Z