The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization. - Wikidata - awgldk - TriplyDB

The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization.

The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization.

http://www.wikidata.org/entity/Q34325524

about

The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease miR-126 regulates angiogenic signaling and vascular integrity Spred1 and TESK1--two new interaction partners of the kinase MARKK/TAO1 that link the microtubule and actin cytoskeleton The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis CXCR4 regulates the early extravasation of metastatic tumor cells in vivo MicroRNA-1 enhances the angiogenic differentiation of human cardiomyocyte progenitor cells.The VASP-Spred-Sprouty domain puzzle.Spred1, a negative regulator of Ras-MAPK-ERK, is enriched in CNS germinal zones, dampens NSC proliferation, and maintains ventricular zone structure.Functional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.Spred-1 negatively regulates interleukin-3-mediated ERK/mitogen-activated protein (MAP) kinase activation in hematopoietic cells.Gene disruption of Spred-2 causes dwarfism.Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1-like phenotype.MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy.Spred2 modulates the erythroid differentiation induced by imatinib in chronic myeloid leukemia cells Spreds are essential for embryonic lymphangiogenesis by regulating vascular endothelial growth factor receptor 3 signaling.Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation SPRED1 Interferes with K-ras but Not H-ras Membrane Anchorage and Signaling.Oxidized low-density lipoprotein is a common risk factor for cardiovascular diseases and gastroenterological cancers via epigenomical regulation of microRNA-210 Interaction between a Domain of the Negative Regulator of the Ras-ERK Pathway, SPRED1 Protein, and the GTPase-activating Protein-related Domain of Neurofibromin Is Implicated in Legius Syndrome and Neurofibromatosis Type 1.Legius Syndrome: two novel mutations in the SPRED1 gene.The neurofibromin recruitment factor Spred1 binds to the GAP related domain without affecting Ras inactivation Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death.Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer.Review and update of SPRED1 mutations causing Legius syndrome.Loss of Sprouty2 in human high-grade serous ovarian carcinomas promotes EGF-induced E-cadherin down-regulation and cell invasion.LacZ transgene expression in the subcutaneous Dunn/LM8 osteosarcoma mouse model allows for the identification of micrometastasis.SPRED proteins provide a NF-ty link to Ras suppression A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1.Spred2 inhibits TGF-beta1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition.SPRED1, a RAS MAPK pathway inhibitor that causes Legius syndrome, is a tumour suppressor downregulated in paediatric acute myeloblastic leukaemia.SPREDs (Sprouty related proteins with EVH1 domain) promote self-renewal and inhibit mesodermal differentiation in murine embryonic stem cells.Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer.Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells.Identification of SPRED1 deletions using RT-PCR, multiplex ligation-dependent probe amplification and quantitative PCR.

P2860

Q24293871-2B613917-4C4D-4220-905C-9BA0EDC9C191 Q24569770-51977974-9D0D-42F3-AAF0-724BF7C4C07B Q24656932-FB5C38F2-85CD-4BE2-B896-085097038C74 Q24656947-191214AB-72B2-42E2-9993-B72932F8128A Q30488263-18AA2AC9-6160-45C7-9539-9FBF4C79C627 Q32884452-6E8C0026-D683-434F-9ACE-6F46ED2F8BB6 Q33343173-84A25138-FA3A-4639-A9C0-1628BD15FF8A Q33573588-22DA30EC-2155-4079-84BB-43E5467AB974 Q34067681-EFE3BB06-E24F-4BA9-88E0-366F8AF68200 Q34355754-BF56FE84-5D03-41B4-AA81-0DC0B992A6D2 Q34425218-196F4306-ACBA-4D6E-933D-9B30FD3977E4 Q34664172-F1C99F2D-F519-4E37-977E-E96994417468 Q34719895-8B0D68F5-0596-4E57-869B-478C73BD1614 Q35092057-070A37B1-DEA6-4324-87D1-014C6C65C3EE Q35857107-F27ACBC0-AE9B-4DD2-BC93-1A9444118D95 Q36050683-AD2852EC-FE10-4B34-9A21-6B98066B0B47 Q36098356-451E611F-5DC7-45CE-B97D-61A20B687920 Q36414391-F87C6992-A2D8-48CB-9FBE-89FEC42891A6 Q36573914-0D05C224-2E35-4220-8FBA-7E53B84491B9 Q36671279-7453D2BA-AD58-4162-857D-72D26C26419F Q37086476-9AE1399D-EA89-4FE3-B66A-CDF126E2C6B6 Q37295451-7021DDCE-337C-42F7-954F-CBDFFD153645 Q37684176-99D53970-A046-48E8-B364-DDCC235669CB Q38023296-1B0B7308-71E7-4A8B-8571-657827D2314F Q38926129-23A07405-557E-474A-A68A-33E0524915EC Q39599601-DC0595F1-BA08-4296-878F-2BE2471BB688 Q41774598-C68F03E9-2C88-4E6F-9A46-BC5BB270A547 Q41877584-EB26A846-4DF0-4127-ADFC-E119ED9FC3D4 Q43622003-03883217-9383-4A74-ABA4-DE664A3A7E0A Q48332997-5E0421BC-52F1-4941-9EE2-79DF00D2439B Q50600489-4B4D4C66-6193-4725-BAD3-61ADC184E015 Q52569162-0627BB8B-FE31-4800-852A-F6392A6B97BA Q53208367-74BAC64D-5290-401F-A9D3-BD7E4FA777A6 Q54374377-E21C29A5-F4B5-4C4F-8FE8-748B754CC7E6

P2860

The Sprouty-related protein, Spred, inhibits cell motility, metastasis, and Rho-mediated actin reorganization.

http://www.wikidata.org/entity/Q34325524

description

2004 nî lūn-bûn

@nan

2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

The Sprouty-related protein, S ...... mediated actin reorganization.

@ast

The Sprouty-related protein, S ...... mediated actin reorganization.

@en

The Sprouty-related protein, S ...... mediated actin reorganization.

@nl

type

label

The Sprouty-related protein, S ...... mediated actin reorganization.

@ast

The Sprouty-related protein, S ...... mediated actin reorganization.

@en

The Sprouty-related protein, S ...... mediated actin reorganization.

@nl

prefLabel

The Sprouty-related protein, S ...... mediated actin reorganization.

@ast

The Sprouty-related protein, S ...... mediated actin reorganization.

@en

The Sprouty-related protein, S ...... mediated actin reorganization.

@nl

P1433

Q34325524-0EE2ADAC-F4A0-4A78-A311-F655932FD008

P1476

Q34325524-84BEC18C-C507-426A-BAB8-5265B0762735

P2093

Q34325524-04FEA7D4-37BA-4462-83FA-FFA3EDA7BFE6

Q34325524-07027202-1372-469D-B4F2-95F765808349

Q34325524-343C85A3-273D-420D-B28F-7198B57EBA3B

Q34325524-6583ED3A-310A-47CC-AEF5-CE78DF69F754

Q34325524-8FC46258-C79E-467E-BA5F-3CB89D539329

Q34325524-A09653E4-E830-4C4B-A03C-3B748C9FDA6D

Q34325524-BB54E8D9-5D64-4BBE-964D-45C986C3F28B

Q34325524-E34D4929-0D06-4128-9FE6-91125A5AB630

Q34325524-F0AB5E80-7913-467C-85C6-77D8D8D6FA2C

Q34325524-F5D91983-17F5-49B2-9C12-2A71A5E1146F

P2860

Q34325524-09E578E5-A2A9-47FC-AA30-AC474DF3CADB

Q34325524-75461DAE-9C9F-4ED5-86F7-CE05A8B5613D

Q34325524-789C2CC6-D7A2-4640-8DCE-BAE73462643C

Q34325524-80E0222C-4D51-4C32-9C2A-C6BDE5A60558

Q34325524-8C5A00F6-952A-4F39-AF69-955375EC5CFD

Q34325524-9E0491BA-DB48-4647-93AB-81F910076A64

Q34325524-A0D6A996-77DE-450E-ACCC-73E92DE5F6D4

Q34325524-A4D1750B-17CC-46C9-BA15-32C3D0BC5553

Q34325524-B0FD7EEC-B307-433E-BF97-BDB2434C74DE

Q34325524-C9AE99E6-BE7A-427A-BF23-1FAC74989852

P2888

Q34325524-BE82F6CC-C3C5-42B6-9E89-C8D7AB605FAF

P304

Q34325524-B6D6A5E8-D763-40E7-B1B5-B06C218A4CC7

P31

Q34325524-6EBFD45D-2E17-4D28-A10E-4A20ED617B0F

P356

Q34325524-ACECA7FB-1BAC-40CF-8324-21B551DB2951

P407

Q34325524-100B6186-1F28-4E8C-A8AC-035EEB1C7C28

P433

Q34325524-A9676286-A699-4269-9305-193B0B48A9C5

P478

Q34325524-71A0B1EC-C415-43AB-BFE6-CD26B9150614

P577

Q34325524-15B11A7F-8F6E-4177-9971-19B690598151

P5875

Q34325524-49381FE8-37F6-4350-9013-2259D27797D4

P6179

Q34325524-12DBE0E2-8C4B-4D98-9E43-FFA9BFE2A739

P698

Q34325524-37A354D5-537C-4B14-BF38-DD3620230B58

P356

P1433

P1476

The Sprouty-related protein, S ...... mediated actin reorganization.

@en

P2093

Akihiko Yoshimura

http://www.w3.org/2001/XMLSchema#string

Hitomi Nishinakamura

http://www.w3.org/2001/XMLSchema#string

Kanta Miyoshi

http://www.w3.org/2001/XMLSchema#string

Lu Yang

http://www.w3.org/2001/XMLSchema#string

Makoto Inoue

http://www.w3.org/2001/XMLSchema#string

Mamoru Hasegawa

http://www.w3.org/2001/XMLSchema#string

Masaki Kamio

http://www.w3.org/2001/XMLSchema#string

Setsuro Komiya

http://www.w3.org/2001/XMLSchema#string

Toru Wakioka

http://www.w3.org/2001/XMLSchema#string

Yoshikazu Yonemitsu

http://www.w3.org/2001/XMLSchema#string

P2860

Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia

Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

Regulation and functions of Rho-associated kinase

Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation. Identification of a novel translocation domain

Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation

RhoA signaling via serum response factor plays an obligatory role in myogenic differentiation

Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

Inhibition of angiogenesis by a mouse sprouty protein.

Identification of a dominant negative mutant of Sprouty that potentiates fibroblast growth factor- but not epidermal growth factor-induced ERK activation.

P2888

P304

5567-5576

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1207759

http://www.w3.org/2001/XMLSchema#string

P407

P433

33

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P577

2004-07-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8521959

http://www.w3.org/2001/XMLSchema#string

P6179

1039270576

http://www.w3.org/2001/XMLSchema#string

P698

15184877

http://www.w3.org/2001/XMLSchema#string