SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis
about
The chromokinesin Kid is required for maintenance of proper metaphase spindle size.Stress-induced decrease in TRAF2 stability is mediated by Siah2The RING finger protein Siah-1 regulates the level of the transcriptional coactivator OBF-1The human chromokinesin Kid is a plus end-directed microtubule-based motorHypoxia-induced assembly of prolyl hydroxylase PHD3 into complexes: implications for its activity and susceptibility for degradation by the E3 ligase Siah2Cdc2-mediated phosphorylation of Kid controls its distribution to spindle and chromosomesThe crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal developmentThe coiled-coil domain is the structural determinant for mammalian homologues of Drosophila Sina-mediated degradation of promyelocytic leukemia protein and other tripartite motif proteins by the proteasomeThe second microtubule-binding site of monomeric kid enhances the microtubule affinityThe ubiquitin ligase component Siah1a is required for completion of meiosis I in male miceMolecular cloning and characterization of a RING-H2 finger protein, ANAPC11, the human homolog of yeast Apc11p.siah-1 Protein is necessary for high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation and cell death in Muller cellsDistinct expression patterns of the E3 ligase SIAH-1 and its partner Kid/KIF22 in normal tissues and in the breast tumoral processes.The ubiquitin ligase Siah2 and the hypoxia response.Degradation of the kinesin Kip1p at anaphase onset is mediated by the anaphase-promoting complex and Cdc20pmiR-135A regulates preimplantation embryo development through down-regulation of E3 Ubiquitin Ligase Seven In Absentia Homolog 1A (SIAH1A) expression.Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue.Normal p53 function in primary cells deficient for Siah genes.Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah.Molecular traces of alternative social organization in a termite genome.A binding motif for Siah ubiquitin ligase.Generation and analysis of Siah2 mutant mice.Herpes simplex virus immediate-early protein ICP0 is targeted by SIAH-1 for proteasomal degradation.Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoterSIAH-1 interacts with the Kaposi's sarcoma-associated herpesvirus-encoded ORF45 protein and promotes its ubiquitylation and proteasomal degradation.E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1.Ubiquitin in regulation of spindle apparatus and its positioning: implications in development and disease.Phyllopod acts as an adaptor protein to link the sina ubiquitin ligase to the substrate protein tramtrackXkid is degraded in a D-box, KEN-box, and A-box-independent pathway.Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR.Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation.The E3 ubiquitin ligase Siah-1 suppresses avian reovirus infection by targeting p10 for degradation.MGRN1-mediated ubiquitination of α-tubulin regulates microtubule dynamics and intracellular transport.Up-regulation of Siah1 by ethanol triggers apoptosis in neural crest cells through p38 MAPK-mediated activation of p53 signaling pathway.Eukaryotic translation elongation factor 1 delta inhibits the ubiquitin ligase activity of SIAH-1.Ectopic expression of the microtubule-dependent motor protein Eg5 promotes pancreatic tumourigenesis
P2860
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P2860
SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis
description
2000 nî lūn-bûn
@nan
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@ast
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@en
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@nl
type
label
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@ast
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@en
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@nl
prefLabel
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@ast
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@en
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@nl
P2093
P2860
P356
P1433
P1476
SIAH-1 interacts with alpha-tu ...... teasome pathway during mitosis
@en
P2093
H Bruzzoni-Giovanelli
N Varin-Blank
S Gisselbrecht
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204002
P407
P577
2000-12-07T00:00:00Z
P5875
P6179
1044439989