Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation
about
Activation of multiple proto-oncogenic tyrosine kinases in breast cancer via loss of the PTPN12 phosphataseABL tyrosine kinases: evolution of function, regulation, and specificityProline-serine-threonine phosphatase interacting proteinĀ 1 inhibition of T-cell receptor signaling depends on its SH3 domainWerner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distributionHaploid genetic screens in human cells identify host factors used by pathogensThe human phosphatase interactome: An intricate family portraitPyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathwayRole of ABL family kinases in cancer: from leukaemia to solid tumoursThe F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages.Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.Caspase-3 regulates catalytic activity and scaffolding functions of the protein tyrosine phosphatase PEST, a novel modulator of the apoptotic response.Caspase-dependent cleavage of c-Abl contributes to apoptosis.Identification of a filamin docking site on PTP-PEST.Binding of the intracellular Fas ligand (FasL) domain to the adaptor protein PSTPIP results in a cytoplasmic localization of FasL.Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation.Pyrin Modulates the Intracellular Distribution of PSTPIP1.PTP-PEST controls motility, adherens junction assembly, and Rho GTPase activity in colon cancer cells.Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phosphatase BDP1.Mutual regulation of protein-tyrosine phosphatase 20 and protein-tyrosine kinase Tec activities by tyrosine phosphorylation and dephosphorylation.Clinical, Molecular, and Genetic Characteristics of PAPA Syndrome: A Review.Identification of Genes That Modulate Susceptibility to Formaldehyde and Imatinib by Functional Genomic Screening in Human Haploid KBM7 Cells.Essential function of PTP-PEST during mouse embryonic vascularization, mesenchyme formation, neurogenesis and early liver development.Activation of abl family kinases in solid tumors.Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.Protein tyrosine phosphatase function: the substrate perspective.TCR-induced downregulation of protein tyrosine phosphatase PEST augments secondary T cell responsesRegulation of tumor cell migration by protein tyrosine phosphatase (PTP)-proline-, glutamate-, serine-,and threonine-rich sequence (PEST).Protein kinase G increases antioxidant function in lung microvascular endothelial cells by inhibiting the c-Abl tyrosine kinase.Signaling networks regulating leukocyte podosome dynamics and function.PAPA, PASH and PAPASH Syndromes: Pathophysiology, Presentation and Treatment.Linking up at the BAR: Oligomerization and F-BAR protein function.c-Abl is an effector of Src for growth factor-induced c-myc expression and DNA synthesis.Distinct roles of c-Abl and Atm in oxidative stress response are mediated by protein kinase C delta.The effect of colchicine on pyrin and pyrin interacting proteins.Disease activity accounts for long-term efficacy of IL-1 blockers in pyogenic sterile arthritis pyoderma gangrenosum and severe acne syndrome.Dual gene activation and knockout screen reveals directional dependencies in genetic networks.Use of Dominant-Negative/Substrate Trapping PTP Mutations to Search for PTP Interactors/Substrates.
P2860
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P2860
Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation
description
2000 nĆ® lÅ«n-bĆ»n
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2000 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« Ō“Õ„ÕÆÕæÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
2000 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ¤Õ„ÕÆÕæÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2000幓ć®č«ę
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2000幓č«ę
@yue
2000幓č«ę
@zh-hant
2000幓č«ę
@zh-hk
2000幓č«ę
@zh-mo
2000幓č«ę
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2000幓č®ŗę
@wuu
name
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@ast
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@en
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@nl
type
label
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@ast
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@en
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@nl
prefLabel
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@ast
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@en
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@nl
P2093
P921
P1433
P1476
Cytoskeletal protein PSTPIP1 d ...... mediate Abl dephosphorylation
@en
P2093
J F CƓtƩ
M L Tremblay
P304
P356
10.1016/S1097-2765(00)00138-6
P407
P577
2000-12-01T00:00:00Z