Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells
about
DLC-1 operates as a tumor suppressor gene in human non-small cell lung carcinomasDLC-1: a Rho GTPase-activating protein and tumour suppressorDLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanismsThe phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1Deleted in liver cancer-1 (DLC-1): a tumor suppressor not just for liverEpigenetic principles and mechanisms underlying nervous system functions in health and diseaseRecent progress in the study of methylated tumor suppressor genes in gastric cancerAKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activityA novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumorsEffects of structure of Rho GTPase-activating protein DLC-1 on cell morphology and migrationDeleted in liver cancer protein family in human malignancies (Review)Transcriptional induction of DLC-1 gene through Sp1 sites by histone deacetylase inhibitors in gastric cancer cellsLow expression of DLC1 is predictive of poor therapeutic efficiency of fluoropyrimidine and oxaliplatin as adjuvant chemotherapy in gastric cancerCRL4A-FBXW5-mediated degradation of DLC1 Rho GTPase-activating protein tumor suppressor promotes non-small cell lung cancer cell growthDownregulation of DLC-1 gene by promoter methylation during primary colorectal cancer progressionPilot study: alteration of deleted in liver cancer1 and phosphorylated focal adhesion kinase Y397 cytoplasmic expression and the prognostic value in advanced epithelial ovarian carcinomaDLC1 is the principal biologically-relevant down-regulated DLC family member in several cancersHelicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis.Identification of the deleted in liver cancer 1 gene, DLC1, as a candidate meningioma tumor suppressor.Hypermethylation of the DLC1 CpG island does not alter gene expression in canine lymphomaA functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinomaHigh-resolution array-based comparative genomic hybridization of medulloblastomas and supratentorial primitive neuroectodermal tumors.Nuclear-targeted deleted in liver cancer 1 (DLC1) is less efficient in exerting its tumor suppressive activity both in vitro and in vivoAberrant gene promoter methylation of p16, FHIT, CRBP1, WWOX, and DLC-1 in Epstein-Barr virus-associated gastric carcinomas.High-frequency promoter hypermethylation of the deleted in liver cancer-1 gene in multiple myeloma.Significance of genetic variants in DLC1 and their association with hepatocellular carcinomaGenomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer.Identification of DLC-1 expression and methylation status in patients with non-small-cell lung cancer.Deleted in liver cancer-1 inhibits cell growth and tumorigenicity in human pancreatic cancerDifferential methylation pattern of ID4, SFRP1, and SHP1 between acute myeloid leukemia and chronic myeloid leukemiaExpression of deleted in liver cancer 1 and plasminogen activator inhibitor 1 protein in ovarian carcinoma and their clinical significanceBiology of SNU cell lines.Inhibition and termination of physiological responses by GTPase activating proteins.Epigenetic alterations in gastric cancer (Review).Curcumin inhibits growth of human breast cancer cells through demethylation of DLC1 promoter.Epigenetic mechanisms regulating the development of hepatocellular carcinoma and their promise for therapeutics.Inhibitory effects of deleted in liver cancer 1 gene on gallbladder cancer growth through induction of cell cycle arrest and apoptosis.DLC1 as a regulator of proliferation, invasion, cell cycle, and apoptosis in cutaneous squamous cell carcinoma.Effect of FAK, DLC-1 gene expression on OVCAR-3 proliferation.Deleted in liver cancer 1 (DLC1) utilizes a novel binding site for Tensin2 PTB domain interaction and is required for tumor-suppressive function.
P2860
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P2860
Transcriptional silencing of the DLC-1 tumor suppressor gene by epigenetic mechanism in gastric cancer cells
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Transcriptional silencing of t ...... hanism in gastric cancer cells
@ast
Transcriptional silencing of t ...... hanism in gastric cancer cells
@en
Transcriptional silencing of t ...... hanism in gastric cancer cells
@nl
type
label
Transcriptional silencing of t ...... hanism in gastric cancer cells
@ast
Transcriptional silencing of t ...... hanism in gastric cancer cells
@en
Transcriptional silencing of t ...... hanism in gastric cancer cells
@nl
prefLabel
Transcriptional silencing of t ...... hanism in gastric cancer cells
@ast
Transcriptional silencing of t ...... hanism in gastric cancer cells
@en
Transcriptional silencing of t ...... hanism in gastric cancer cells
@nl
P2093
P2860
P3181
P356
P1433
P1476
Transcriptional silencing of t ...... hanism in gastric cancer cells
@en
P2093
Alexandre Dimtchev
Hyun-Soon Jong
Jung Weon Lee
Noe Kyeong Kim
Sang-Hyun Song
Sook-Jung Jeong
Tae-You Kim
Tai Young Kim
Yung-Jue Bang
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1206573
P407
P577
2003-06-19T00:00:00Z
P5875
P6179
1003907431