AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity
about
The molecular effect of metastasis suppressors on Src signaling and tumorigenesis: new therapeutic targetsGravin gene expression in acute leukaemias: clinical importance and review of the literatureEmpowering biologists with multi-omics data: colorectal cancer as a paradigm.SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma.Loss of the SSeCKS/Gravin/AKAP12 gene results in prostatic hyperplasiaRetinoid-induced expression and activity of an immediate early tumor suppressor gene in vascular smooth muscle cells.Re-expression of AKAP12 inhibits progression and metastasis potential of colorectal carcinoma in vivo and in vitroPhosphoproteomic analysis of gossypol-induced apoptosis in ovarian cancer cell line, HOC1a.Alternative splicing in bone following mechanical loading.Emerging Roles for SSeCKS/Gravin/AKAP12 in the Control of Cell Proliferation, Cancer Malignancy, and Barriergenesis.Ensemble of gene signatures identifies novel biomarkers in colorectal cancer activated through PPARγ and TNFα signalingHypoxic induction of AKAP12 variant 2 shifts PKA-mediated protein phosphorylation to enhance migration and metastasis of melanoma cells.Original Research: Analysis of hepatic microRNA alterations in response to hepatitis B virus infection and pegylated interferon alpha-2a treatmentAnchoring of both PKA-RIIα and 14-3-3θ regulates retinoic acid induced 16 mediated phosphorylation of heat shock protein 70.Elevated AKAP12 in paclitaxel-resistant serous ovarian cancer cells is prognostic and predictive of poor survival in patients.Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia.Evaluation of potential regulatory function of breast cancer risk locus at 6q25.1.Biology of SNU cell lines.Suppression of tumor and metastasis progression through the scaffolding functions of SSeCKS/Gravin/AKAP12A-kinase anchoring proteins: cAMP compartmentalization in neurodegenerative and obstructive pulmonary diseases.A ChIP-chip approach reveals a novel role for transcription factor IRF1 in the DNA damage response.Epigenetic alterations in gastric cancer (Review).Scaffolding during the cell cycle by A-kinase anchoring proteins.Expression of core 3 synthase in human pancreatic cancer cells suppresses tumor growth and metastasis.Identification of the A kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma.Gene silencing of TSPYL5 mediated by aberrant promoter methylation in gastric cancers.AKAP12alpha is associated with promoter methylation in lung cancer.Frequent reduced expression of alpha-1B-adrenergic receptor caused by aberrant promoter methylation in gastric cancers.Examination of AKAP12 promoter methylation in skin cancer using methylation-sensitive high-resolution melting analysis.v-Src-mediated down-regulation of SSeCKS metastasis suppressor gene promoter by the recruitment of HDAC1 into a USF1-Sp1-Sp3 complex.Identification of key miRNA-gene pairs in chronic lymphocytic leukemia through integrated analysis of mRNA and miRNA microarray.Kinome and phosphoproteome of high-grade meningiomas reveal AKAP12 as a central regulator of aggressiveness and its possible role in progression.Gravin gene expression in acute myeloid leukemia.The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells.AKAP12, a gene with tumour suppressor properties, is a target of promoter DNA methylation in childhood myeloid malignancies.Mithramycin A Alleviates Osteoarthritic Cartilage Destruction by Inhibiting HIF-2α Expression.A-kinase anchoring protein 12 is downregulated in human hepatocellular carcinoma and its deficiency in mice aggravates thioacetamide-induced liver injury
P2860
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P2860
AKAP12/Gravin is inactivated by epigenetic mechanism in human gastric carcinoma and shows growth suppressor activity
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@ast
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@en
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@nl
type
label
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@ast
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@en
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@nl
prefLabel
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@ast
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@en
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@nl
P2093
P2860
P356
P1433
P1476
AKAP12/Gravin is inactivated b ...... ows growth suppressor activity
@en
P2093
Dong Soon Lee
Hyun-Soon Jong
Jung Weon Lee
Moon-Chang Choi
Noe Kyeong Kim
Sang-Hyun Song
Tae-You Kim
Tai Young Kim
Yung-Jue Bang
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207932
P407
P577
2004-09-16T00:00:00Z
P5875
P6179
1025339350