Effects of D3.49A, R3.50A, and A6.34E mutations on ligand binding and activation of the cannabinoid-2 (CB2) receptor
about
Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligandsUnderstanding functional residues of the cannabinoid CB1.Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effectsDissimilar interaction of CB1/CB2 with lipid bilayers as revealed by molecular dynamics simulation.hCB2 ligand-interaction landscape: cysteine residues critical to biarylpyrazole antagonist binding motif and receptor modulation.Structural basis of G protein-coupled receptor-Gi protein interaction: formation of the cannabinoid CB2 receptor-Gi protein complexRole of Endocannabinoid Activation of Peripheral CB1 Receptors in the Regulation of Autoimmune Disease.Identification of raloxifene as a novel CB2 inverse agonist.Species differences in cannabinoid receptor 2 and receptor responses to cocaine self-administration in mice and ratsCharacterization of G protein coupling mediated by the conserved D134(3.49) of DRY motif, M241(6.34), and F251(6.44) residues on human CXCR1.Targeting the CB2 receptor for immune modulation.Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations.Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.CB2 cannabinoid receptor is a novel target for third-generation selective estrogen receptor modulators bazedoxifene and lasofoxifene.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.The importance of hydrogen bonding and aromatic stacking to the affinity and efficacy of cannabinoid receptor CB2 antagonist, 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-
P2860
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P2860
Effects of D3.49A, R3.50A, and A6.34E mutations on ligand binding and activation of the cannabinoid-2 (CB2) receptor
description
2003 nî lūn-bûn
@nan
2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@ast
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@en
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
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type
label
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@ast
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@en
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@nl
prefLabel
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@ast
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@en
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@nl
P921
P1476
Effects of D3.49A, R3.50A, and ...... e cannabinoid-2 (CB2) receptor
@en
P2093
P304
P356
10.1016/S0006-2952(03)00005-4
P407
P577
2003-04-01T00:00:00Z