The structural requirements for ceramide activation of serine-threonine protein phosphatases
about
Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's diseaseTargeting protein serine/threonine phosphatases for drug developmentSphingolipid signaling in metabolic disordersA review of ceramide analogs as potential anticancer agentsRegulation of PP2A by Sphingolipid Metabolism and SignalingCeramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid LeukemiaCeramides in Alzheimer's Disease: Key Mediators of Neuronal Apoptosis Induced by Oxidative Stress and Aβ AccumulationA metabolic shift favoring sphingosine 1-phosphate at the expense of ceramide controls glioblastoma angiogenesis.Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain developmentRe-configuration of sphingolipid metabolism by oncogenic transformation.Control of death-associated protein kinase (DAPK) activity by phosphorylation and proteasomal degradationBacterial Sphingomyelinase is a State-Dependent Inhibitor of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR)Protein phosphatase 2A (PP2A) holoenzymes regulate death-associated protein kinase (DAPK) in ceramide-induced anoikis.The membrane and lipids as integral participants in signal transduction: lipid signal transduction for the non-lipid biochemist.Ceramide modulates pre-mRNA splicing to restore the expression of wild-type tumor suppressor p53 in deletion-mutant cancer cells.Attacking the supply wagons to starve cancer cells to death.Complexation of c6-ceramide with cholesteryl phosphocholine - a potent solvent-free ceramide delivery formulation for cells in culture.Synthesis and characterization of pseudocantharidins, novel phosphatase modulators that promote the inclusion of exon 7 into the SMN (survival of motoneuron) pre-mRNARegulation of phosphatidic Acid metabolism by sphingolipids in the central nervous systemCoupling in vitro and in vivo paradigm reveals a dose dependent inhibition of angiogenesis followed by initiation of autophagy by C6-ceramide.Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1betaCeramide channels: influence of molecular structure on channel formation in membranesIt's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation.Ceramide channel: Structural basis for selective membrane targeting.Novel analogs of D-e-MAPP and B13. Part 2: signature effects on bioactive sphingolipids.Combined therapeutic use of AdGFPFasL and small molecule inhibitors of ceramide metabolism in prostate and head and neck cancers: a status report.Identification and characterization of protein phosphatase 2C activation by ceramide.Remodeling of cellular cytoskeleton by the acid sphingomyelinase/ceramide pathwayCeramide limits phosphatidylinositol-3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide as a metastasis-suppressor lipidCeramide signaling in cancer and stem cells.Sorafenib and pemetrexed toxicity in cancer cells is mediated via SRC-ERK signalingSmart drugs for smarter stem cells: making SENSe (sphingolipid-enhanced neural stem cells) of ceramide.Akt2 and acid ceramidase cooperate to induce cell invasion and resistance to apoptosisDirect interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signalingCeramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cellsMembrane signaling induced by high doses of ionizing radiation in the endothelial compartment. Relevance in radiation toxicity.Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathways.Lipid second messengers and related enzymes in vertebrate rod outer segments.Ceramide signaling in mammalian epidermis.Phosphorylation of a constrained azacyclic FTY720 analog enhances anti-leukemic activity without inducing S1P receptor activation.
P2860
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P2860
The structural requirements for ceramide activation of serine-threonine protein phosphatases
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
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2004 թվականի մարտին հրատարակված գիտական հոդված
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2004年の論文
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2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The structural requirements fo ...... threonine protein phosphatases
@ast
The structural requirements fo ...... threonine protein phosphatases
@en
The structural requirements fo ...... threonine protein phosphatases
@nl
type
label
The structural requirements fo ...... threonine protein phosphatases
@ast
The structural requirements fo ...... threonine protein phosphatases
@en
The structural requirements fo ...... threonine protein phosphatases
@nl
prefLabel
The structural requirements fo ...... threonine protein phosphatases
@ast
The structural requirements fo ...... threonine protein phosphatases
@en
The structural requirements fo ...... threonine protein phosphatases
@nl
P2093
P2860
P1476
The structural requirements fo ...... threonine protein phosphatases
@en
P2093
Alicja Bielawska
Charles E Chalfant
Patrick Roddy
Zdzislaw Szulc
P2860
P304
P356
10.1194/JLR.M300347-JLR200
P407
P577
2004-03-01T00:00:00Z