Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging - Wikidata - awgldk - TriplyDB

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

http://www.wikidata.org/entity/Q28191739

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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans Replicative senescence induced by Romo1-derived reactive oxygen species Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice Oxidative stress, mitochondrial dysfunction, and aging Is the oxidative stress theory of aging dead?Insulin resistance is a cellular antioxidant defense mechanism SIRT6 in DNA repair, metabolism and ageing Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck Oxidative stress and adult neurogenesis--effects of radiation and superoxide dismutase deficiency SOD2 deficiency promotes aging phenotypes in mouse skin Mitochondrial ROS in cancer: initiators, amplifiers or an Achilles' heel?Oxidative stress and diabetes: what can we learn about insulin resistance from antioxidant mutant mouse models?Hormesis in aging and neurodegeneration-a prodigy awaiting dissection Manganese activation of superoxide dismutase 2 in the mitochondria of Saccharomyces cerevisiae.Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!The hallmarks of aging Multiple measures of functionality exhibit progressive decline in a parallel, stochastic fashion in Drosophila Sod2 null mutants Mitochondrial hormesis and diabetic complications Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling The Roles of Glutathione Peroxidases during Embryo Development Elevated mitochondrial oxidative stress impairs metabolic adaptations to exercise in skeletal muscle Generation and characterisation of Friedreich ataxia YG8R mouse fibroblast and neural stem cell models Testing predictions of the oxidative stress hypothesis of aging using a novel invertebrate model of longevity: the giant clam (Tridacna derasa)Aging and the Mammalian regulatory triumvirate Correlates of substitution rate variation in mammalian protein-coding sequences A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine ROS function in redox signaling and oxidative stress Oxidative stress and neurodegeneration: where are we now?Attenuation of liver insoluble protein carbonyls: indicator of a longevity determinant?DNA replication stress is a determinant of chronological lifespan in budding yeast.The role of mitochondrial DNA mutations in mammalian aging Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program.Mitochondrial oxidative stress causes hyperphosphorylation of tau.Association between SOD2 T-9C and MTHFR C677T polymorphisms and longevity: a study in Jordanian population Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis Decreased superoxide production in macrophages of long-lived p66Shc knock-out mice.Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?Age-dependent increases in interstitial collagenase and MAP Kinase levels are exacerbated by superoxide dismutase deficiencies Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans.Calorie restriction and cancer prevention: metabolic and molecular mechanisms.

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P2860

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

http://www.wikidata.org/entity/Q28191739

description

2003 nî lūn-bûn

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2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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Life-long reduction in MnSOD a ...... but does not accelerate aging

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Life-long reduction in MnSOD a ...... but does not accelerate aging

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Life-long reduction in MnSOD a ...... but does not accelerate aging

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Life-long reduction in MnSOD a ...... but does not accelerate aging

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PHYSIOLGENOMICS.00122.2003

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Physiological Genomics

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Life-long reduction in MnSOD a ...... but does not accelerate aging

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Arlan Richardson

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Charles J Epstein

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John W Baynes

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2694030

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10.1152/PHYSIOLGENOMICS.00122.2003

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Holly Van Remmen

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2003-12-16T00:00:00Z

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8956658

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