Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity

Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity

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http://www.wikidata.org/entity/Q28195554
Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2The Binding and Release of Oxygen and Hydrogen Peroxide Are Directed by a Hydrophobic Tunnel in Cholesterol Oxidase †Structural Basis of Fatty Acid Substrate Binding to Cyclooxygenase-2A comparative analysis of clustering algorithms: O2 migration in truncated hemoglobin I from transition networks.Molecular dioxygen enters the active site of 12/15-lipoxygenase via dynamic oxygen access channelsEnzyme Tunnels and Gates As Relevant Targets in Drug Design.Control of oxygenation in lipoxygenase and cyclooxygenase catalysisProstaglandin H synthase: resolved and unresolved mechanistic issues.Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-acyl hydrazone subunit.Lipoxygenase 2 from Cyanothece sp. controls dioxygen insertion by steric shielding and substrate fixation.
P2860

Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity

Item
http://www.wikidata.org/entity/Q28195554
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
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2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
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2006年論文
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2006年论文
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name
Molecular dynamics simulations ...... n regio- and stereoselectivity
@ast
Molecular dynamics simulations ...... n regio- and stereoselectivity
@en
Molecular dynamics simulations ...... n regio- and stereoselectivity
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type
label
Molecular dynamics simulations ...... n regio- and stereoselectivity
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Molecular dynamics simulations ...... n regio- and stereoselectivity
@en
Molecular dynamics simulations ...... n regio- and stereoselectivity
@nl
prefLabel
Molecular dynamics simulations ...... n regio- and stereoselectivity
@ast
Molecular dynamics simulations ...... n regio- and stereoselectivity
@en
Molecular dynamics simulations ...... n regio- and stereoselectivity
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Molecular dynamics simulations ...... n regio- and stereoselectivity
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932