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Binding isotope effects: boon and baneTransition-state inhibitors of purine salvage and other prospective enzyme targets in malariaPlasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal modelClosed site complexes of adenine phosphoribosyltransferase from Giardia lamblia reveal a mechanism of ribosyl migrationInhibition and Structure of Trichomonas vaginalis Purine Nucleoside Phosphorylase with Picomolar Transition State Analogues †Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-ANeighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibitionl -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside PhosphorylaseStructural Insights into Intermediate Steps in the Sir2 Deacetylation ReactionTransition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.A phosphoenzyme mimic, overlapping catalytic sites and reaction coordinate motion for human NAMPTStructural and Metabolic Specificity of Methylthiocoformycin for Malarial Adenosine DeaminasesTransition state analogues in structures of ricin and saporin ribosome-inactivating proteinsMethylthioinosine Phosphorylase from Pseudomonas aeruginosa . Structure and Annotation of a Novel Enzyme in Quorum SensingA High-Affinity Adenosine Kinase from Anopheles gambiaeA Picomolar Transition State Analogue Inhibitor of MTAN as a Specific Antibiotic for Helicobacter pyloriMethylthioadenosine Deaminase in an Alternative Quorum Sensing Pathway in Pseudomonas aeruginosaCatalytic site conformations in human PNP by 19F-NMR and crystallography.Salmonella enterica MTAN at 1.36 Å Resolution: A Structure-Based Design of Tailored Transition State AnalogsAcyclic Immucillin Phosphonates: Second-Generation Inhibitors of Plasmodium falciparum Hypoxanthine- Guanine-Xanthine PhosphoribosyltransferaseInhibition and Structure of Toxoplasma gondii Purine Nucleoside PhosphorylaseStructural and biochemical characterization of Chlamydia trachomatis hypothetical protein CT263 supports that menaquinone synthesis occurs through the futalosine pathway.Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillinsMalaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Vern L Schramm
@ast
Vern L Schramm
@en
Vern L Schramm
@es
Vern L Schramm
@sl
type
label
Vern L Schramm
@ast
Vern L Schramm
@en
Vern L Schramm
@es
Vern L Schramm
@sl
prefLabel
Vern L Schramm
@ast
Vern L Schramm
@en
Vern L Schramm
@es
Vern L Schramm
@sl
P106
P21
P31
P569
2000-01-01T00:00:00Z