Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
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Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formationAn extended consensus motif enhances the specificity of substrate modification by SUMOStructure of Importin13-Ubc9 complex: nuclear import and release of a key regulator of sumoylationStructures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1SUMO modification of human XRCC4 regulates its localization and function in DNA double-strand break repair.SUMO protease SENP1 induces isomerization of the scissile peptide bondUbiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathwaysStructure and Analysis of a Complex between SUMO and Ubc9 Illustrates Features of a Conserved E2-Ubl InteractionStructure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO PathwayThe Intrinsic Affinity between E2 and the Cys Domain of E1 in Ubiquitin-like ModificationsMolecular mimicry of SUMO promotes DNA repairDNA Repair and Global Sumoylation Are Regulated by Distinct Ubc9 Noncovalent ComplexesStructural basis for catalytic activation by the human ZNF451 SUMO E3 ligaseUnique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selectionStructural and dynamic independence of isopeptide-linked RanGAP1 and SUMO-1SUMO Ubc9 enzyme as a viral targetIs Transthyretin a Regulator of Ubc9 SUMOylation?BubR1 is modified by sumoylation during mitotic progressionSumoylation-independent activation of Calcineurin-NFAT-signaling via SUMO2 mediates cardiomyocyte hypertrophy.Exploring structural variability in X-ray crystallographic models using protein local optimization by torsion-angle samplingE2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex.Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction.Development of FRET assay into quantitative and high-throughput screening technology platforms for protein-protein interactions.Sparse estimation for structural variability.RWD Domain as an E2 (Ubc9)-Interaction Module.Small ubiquitin-like modifier (SUMO) modification of E1 Cys domain inhibits E1 Cys domain enzymatic activity.SUMO deconjugation is required for arsenic-triggered ubiquitylation of PMLTargeting Ubc9 for cancer therapy.Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathwayProtection from isopeptidase-mediated deconjugation regulates paralog-selective sumoylation of RanGAP1.Protein interactions in the sumoylation cascade: lessons from X-ray structures.Identification of a SUMO-binding motif that recognizes SUMO-modified proteins.The enzymes in ubiquitin-like post-translational modifications.Ubiquitin-like Protein Conjugation: Structures, Chemistry, and Mechanism.Concepts and Methodologies to Study Protein SUMOylation: An Overview.Highly sensitive assays for SUMOylation and small ubiquitin-like modifier-dependent protein-protein interactions.Design of high-throughput screening assays and identification of a SUMO1-specific small molecule chemotype targeting the SUMO-interacting motif-binding surface.Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulationStability of thioester intermediates in ubiquitin-like modificationsEntropy-driven mechanism of an E3 ligase
P2860
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P2860
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
description
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im August 2003 veröffentlicher wissenschaftlicher Artikel
@de
scientific article (publication date: 26 August 2003)
@en
vedecký článok (publikovaný 2003/08/26)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/08/26)
@nl
наукова стаття, опублікована в серпні 2003
@uk
مقالة علمية (نشرت في 26-8-2003)
@ar
name
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@ast
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@en
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@nl
type
label
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@ast
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@en
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@nl
prefLabel
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@ast
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@en
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@nl
P2093
P3181
P356
P1433
P1476
Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation
@en
P2093
Ellis Jaffray
Jian Zheng
Manuel S Rodriguez
Suhkmann Kim
P304
P3181
P356
10.1021/BI0345283
P407
P577
2003-08-26T00:00:00Z