Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism
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Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificitiesParaoxonase 1 (PON1) as a genetic determinant of susceptibility to organophosphate toxicityThe human paraoxonase gene cluster as a target in the treatment of atherosclerosisAssociation of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American womenHuman paraoxonase-1 (PON1): Gene structure and expression, promiscuous activities and multiple physiological rolesGenetic susceptibility to lymphomaDietary squalene increases high density lipoprotein-cholesterol and paraoxonase 1 and decreases oxidative stress in miceDietary polyphenols increase paraoxonase 1 gene expression by an aryl hydrocarbon receptor-dependent mechanism.Towards a strategic approaches in alternative tests for pesticide safety.Association of Paraoxonase 1 (PON1) polymorphisms with osteoporotic fracture risk in postmenopausal Korean women.Pharmacological and dietary modulators of paraoxonase 1 (PON1) activity and expression: the hunt goes on.Effects of intronic and exonic polymorphisms of paraoxonase 1 (PON1) gene on serum PON1 activity in a Korean populationParaoxonase 1, agricultural organophosphate exposure, and Parkinson diseaseChicory (Cichorium intybus L.) root extract regulates the oxidative status and antioxidant gene transcripts in CCl4-induced hepatotoxicity.Human valacyclovir hydrolase/biphenyl hydrolase-like protein is a highly efficient homocysteine thiolactonase.Association of paraoxonase 1 gene polymorphism and enzyme activity with carotid plaque in rheumatoid arthritis.The effect of Omega-3 fatty acids on serum paraoxonase activity, vitamins A, E, and C in type 2 diabetic patientsPlasma proteomic profiles from disease-discordant monozygotic twins suggest that molecular pathways are shared in multiple systemic autoimmune diseases.Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192Hormonal and chemical regulation of paraoxonases in miceAssociation of paraoxonase activity and atherosclerosis in patients with chronic hepatitis B.A long and winding road: defining the biological role and clinical importance of paraoxonases.Interspecies Differences in the Metabolism of a Multiester Prodrug by CarboxylesterasesRole of genetic changes in the progression of cardiovascular diseases.Targeted Proteomics Identifies Paraoxonase/Arylesterase 1 (PON1) and Apolipoprotein Cs as Potential Risk Factors for Hypoalphalipoproteinemia in Diabetic Subjects Treated with Fenofibrate and Rosiglitazone.Relationship of human paraoxonase-1 serum activity and genotype with atherosclerosis in individuals from the Deep SouthPON1 multitasks to protect health.Serum Paraoxonase (PON1) Activity in North-West Indian Punjabi's with Acute Myocardial InfarctionFunctional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposureAssociations between high density lipoprotein mean particle size and serum paraoxonase-1 activitySerum paraoxonase 1 activity is associated with fatty acid composition of high density lipoprotein.Localization of multiple pleiotropic genes for lipoprotein metabolism in baboons.Characterization of human paraoxonase 1 variants suggest that His residues at 115 and 134 positions are not always needed for the lactonase/arylesterase activities of the enzyme.PEP-1-PON1 protein regulates inflammatory response in raw 264.7 macrophages and ameliorates inflammation in a TPA-induced animal model.The Early Effect of Carotid Artery Stenting on Antioxidant Capacity and Oxidative Stress in Patients with Carotid Artery StenosisParaoxonase-1 (PON1) rs662 Polymorphism and Its Association with Serum Lipid Levels and Longevity in the Bama Zhuang PopulationParaoxonase-2 (PON2) in brain and its potential role in neuroprotection.Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics studyResveratrol commonly displays hormesis: occurrence and biomedical significance.Organophosphate pesticides and PON1 L55M in Parkinson's disease progression.
P2860
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P2860
Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism
description
2003 nî lūn-bûn
@nan
2003 թուականին հրատարակուած գիտական յօդուած
@hyw
2003 թվականին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Functional genomic of the para ...... r disease, and drug metabolism
@ast
Functional genomic of the para ...... r disease, and drug metabolism
@en
Functional genomic of the para ...... r disease, and drug metabolism
@nl
type
label
Functional genomic of the para ...... r disease, and drug metabolism
@ast
Functional genomic of the para ...... r disease, and drug metabolism
@en
Functional genomic of the para ...... r disease, and drug metabolism
@nl
prefLabel
Functional genomic of the para ...... r disease, and drug metabolism
@ast
Functional genomic of the para ...... r disease, and drug metabolism
@en
Functional genomic of the para ...... r disease, and drug metabolism
@nl
P2093
P1476
Functional genomic of the para ...... r disease, and drug metabolism
@en
P2093
Clement E Furlong
Lucio G Costa
Toby B Cole
P304
P356
10.1146/ANNUREV.MED.54.101601.152421
P407
P577
2003-01-01T00:00:00Z