Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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N-(Pivaloyloxy)alkoxy-carbonyl Prodrugs of the Glutamine Antagonist 6-Diazo-5-oxo-l-norleucine (DON) as a Potential Treatment for HIV Associated Neurocognitive Disorders.

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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P1476

Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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P2093

Erik Pacyniak

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Jing Fu

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Lesley Marson

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Marina G D Leed

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Matthew P Sadgrove

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Michael Jay

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Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism

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Human carboxylesterase isozymes: catalytic properties and rational drug design

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Establishing efficacy of human products using animals: the US food and drug administration's "animal rule".

Hydrolysis of irinotecan and its oxidative metabolites, 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxycamptothecin and 7-ethyl-10-[4-(1-piperidino)-1-amino]-carbonyloxycamptothecin, by human carboxylesterases CES1A1, CES2, and a n

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989-995

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scholarly article

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10.1002/JPS.24632

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English

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105

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2015-09-07T00:00:00Z

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4781669

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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P2860

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Interspecies Differences in the Metabolism of a Multiester Prodrug by Carboxylesterases

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P1433

P1476

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P2860

P304

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P433

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P1476

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P304

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P407

P433

P478

P577

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