The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
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The expression of the ubiquitin ligase subunit Cks1 in human breast cancerSilencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinomaRegulation of p27 degradation and S-phase progression by Ro52 RING finger proteinStructural basis of dimerization-dependent ubiquitination by the SCF(Fbx4) ubiquitin ligaseThe stomatin-like protein SLP-1 and Cdk2 interact with the F-Box protein Fbw7-γUbiquitin-independent proteasomal degradation of endoplasmic reticulum-localized connexin43 mediated by CIP75A negatively charged amino acid in Skp2 is required for Skp2-Cks1 interaction and ubiquitination of p27Kip1RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localizationIdentification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17Protein-protein interactions involved in the recognition of p27 by E3 ubiquitin ligaseStress-induced decrease in TRAF2 stability is mediated by Siah2CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysisNovel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functionsSCFSkp2 complex targeted by Epstein-Barr virus essential nuclear antigenSpecific small molecule inhibitors of Skp2-mediated p27 degradationDeregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancerRole of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradationPhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexRole of the F-box protein Skp2 in adhesion-dependent cell cycle progressionThe F-box protein SKP2 mediates androgen control of p27 stability in LNCaP human prostate cancer cells.Deregulation of p27 by oncogenic signaling and its prognostic significance in breast cancerCks confers specificity to phosphorylation-dependent CDK signaling pathwaysDoc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.Function and regulation of cullin-RING ubiquitin ligasesPam and its ortholog highwire interact with and may negatively regulate the TSC1.TSC2 complexThree different binding sites of Cks1 are required for p27-ubiquitin ligationRole of conformational heterogeneity in domain swapping and adapter function of the Cks proteinsMutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cellsAmplification and overexpression of CKS1B at chromosome band 1q21 is associated with reduced levels of p27Kip1 and an aggressive clinical course in multiple myelomaThe SCF ubiquitin ligase: insights into a molecular machinePhospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage responseThe ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transitionp27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysisPhosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligaseCyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cellsThe NEDD8 system is essential for cell cycle progression and morphogenetic pathway in miceGCN5 is a required cofactor for a ubiquitin ligase that targets NF-kappaB/RelAAmyloid precursor protein binding protein-1 modulates cell cycle progression in fetal neural stem cells.Protein stability and function of p73 are modulated by a physical interaction with RanBPM in mammalian cultured cells.The ubiquitin system, disease, and drug discovery.
P2860
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P2860
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@ast
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@en
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@nl
type
label
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@ast
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@en
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@nl
prefLabel
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@ast
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@en
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@nl
P2093
P3181
P356
P1433
P1476
The cell-cycle regulatory prot ...... diated ubiquitinylation of p27
@en
P2093
G Bornstein
P2888
P3181
P356
10.1038/35060126
P407
P577
2001-03-01T00:00:00Z
P6179
1023809615