Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha
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Bile acid transporters in health and diseaseBile acid transportersPeroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzymeApical sodium bile acid transporter and ileal lipid binding protein in gallstone carriersClinical application of transcriptional activators of bile salt transporters.Peroxisome proliferator-activated receptor α activates human multidrug resistance transporter 3/ATP-binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretionAnalysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorptionRole of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene.Cholesterol modulates human intestinal sodium-dependent bile acid transporter.The mechanism of enterohepatic circulation in the formation of gallstone disease.Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor.Regulation of drug and bile salt transporters in liver and intestine.PPARalpha agonist-induced rodent tumors: modes of action and human relevance.Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis.Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences.Fibrates and cholestasisBile acid interactions with cholangiocytes.Metabolomics reveals an essential role for peroxisome proliferator-activated receptor α in bile acid homeostasis.Nuclear receptors as drug targets in cholestatic liver diseases.Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts.Nuclear receptors as therapeutic targets in cholestatic liver diseases.Regulation of bile acid and cholesterol metabolism by PPARsIntestinal bile acid physiology and pathophysiology.c-Fos mediates repression of the apical sodium-dependent bile acid transporter by fibroblast growth factor-19 in miceA single element in the 3'UTR of the apical sodium-dependent bile acid transporter controls both stabilization and destabilization of mRNA.Nuclear-receptor-mediated regulation of drug- and bile-acid-transporter proteins in gut and liver.Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).Meta-analysis of primary target genes of peroxisome proliferator-activated receptors.PPARα activation protects against cholestatic liver injury.Peroxisome proliferator-activated receptor alpha target genes.Consumption of plant sterols reduces plasma and hepatic triglycerides and modulates the expression of lipid regulatory genes and de novo lipogenesis in C57BL/6J mice.Ontogenetic development of rat intestinal bile acid transport requires thyroxine but not corticosterone.Differential regulation of cytosolic and peroxisomal bile acid amidation by PPAR alpha activation favors the formation of unconjugated bile acids.Alterations in bile acid synthesis in carriers of hepatocyte nuclear factor 1α mutations.Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARα-Dependent Manner.Reduced ileal expression of OSTalpha-OSTbeta in non-obese gallstone disease.Fic1 is expressed at apical membranes of different epithelial cells in the digestive tract and is induced in the small intestine during postnatal development of mice.Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptakeRegulation of the gene encoding the intestinal bile acid transporter ASBT by the caudal-type homeobox proteins CDX1 and CDX2
P2860
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P2860
Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human apical sodium-dependent ...... rator-activated receptor alpha
@ast
Human apical sodium-dependent ...... rator-activated receptor alpha
@en
Human apical sodium-dependent ...... rator-activated receptor alpha
@nl
type
label
Human apical sodium-dependent ...... rator-activated receptor alpha
@ast
Human apical sodium-dependent ...... rator-activated receptor alpha
@en
Human apical sodium-dependent ...... rator-activated receptor alpha
@nl
prefLabel
Human apical sodium-dependent ...... rator-activated receptor alpha
@ast
Human apical sodium-dependent ...... rator-activated receptor alpha
@en
Human apical sodium-dependent ...... rator-activated receptor alpha
@nl
P2093
P2860
P356
P1476
Human apical sodium-dependent ...... rator-activated receptor alpha
@en
P2093
Diana Jung
Gerd A Kullak-Ublick
Michael Fried
P2860
P304
P356
10.1074/JBC.M203511200
P407
P577
2002-08-23T00:00:00Z