Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
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Inhibition of MLK3-MKK4/7-JNK1/2 pathway by Akt1 in exogenous estrogen-induced neuroprotection against transient global cerebral ischemia by a non-genomic mechanism in male ratsThe POSH/JIP-1 scaffold network regulates TCR-mediated JNK1 signals and effector function in CD8(+) T cells.POSH misexpression induces caspase-dependent cell death in Drosophila.Regulation of the Pro-apoptotic scaffolding protein POSH by Akt.Genetic modifier screens reveal new components that interact with the Drosophila dystroglycan-dystrophin complex.POSH is an intracellular signal transducer for the axon outgrowth inhibitor Nogo66.Akt-mediated signaling is induced by cytokines and cyclic adenosine monophosphate and suppresses hepatocyte inducible nitric oxide synthase expression independent of MAPK P44/42.Programmed cell death and new discoveries in the genetics of parkinsonism.Insulin inhibits hepatocyte iNOS expression induced by cytokines by an Akt-dependent mechanism.The ubiquitin E3 ligase POSH regulates calcium homeostasis through spatial control of Herp.Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition.Achieving specificity in Akt signaling in cancer.Inhibition of mitogen-activated protein kinase and stimulation of Akt kinase signaling pathways: Two approaches with therapeutic potential in the treatment of neurodegenerative diseaseMixed lineage kinases (MLKs): a role in dendritic cells, inflammation and immunity?The scaffold protein POSH regulates axon outgrowth.The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complexDistinct biological roles for the akt family in mammary tumor progressionGq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation.Regulation of the protein stability of POSH and MLK family.Regulation of apoptotic c-Jun N-terminal kinase signaling by a stabilization-based feed-forward loop.POSH Regulates CD4+ T Cell Differentiation and Survival.Increased expression of Mcl-1 is required for protection against serum starvation in phosphatase and tensin homologue on chromosome 10 null mouse embryonic fibroblasts, but repression of Bim is favored in human glioblastomas.Neuroprotective effects of preconditioning ischaemia on ischaemic brain injury through inhibition of mixed-lineage kinase 3 via NMDA receptor-mediated Akt1 activation.Knock-down of POSH expression is neuroprotective through down-regulating activation of the MLK3-MKK4-JNK pathway following cerebral ischaemia in the rat hippocampal CA1 subfield.POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila.POSH promotes cell survival in Drosophila and in human RASF cells.Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival.
P2860
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P2860
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@ast
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@en
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@nl
type
label
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@ast
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@en
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@nl
prefLabel
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@ast
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@en
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@nl
P2093
P2860
P356
P1476
Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex
@en
P2093
Anne B Vojtek
Claudia Figueroa
Jennifer Taylor
Samantha Tarras
P2860
P304
P356
10.1074/JBC.M307357200
P407
P577
2003-11-28T00:00:00Z