Negative regulation of the serine/threonine kinase B-Raf by Akt - Wikidata - awgldk - TriplyDB

Negative regulation of the serine/threonine kinase B-Raf by Akt

Negative regulation of the serine/threonine kinase B-Raf by Akt

http://www.wikidata.org/entity/Q28139252

about

sameAs

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling Raf family kinases: old dogs have learned new tricks The RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.S338 phosphorylation of Raf-1 is independent of phosphatidylinositol 3-kinase and Pak3 The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms Molecular Targeting of ERKs/RSK2 Signaling Axis in Cancer Prevention Gamma-hydroxybutyrate reduces mitogen-activated protein kinase phosphorylation via GABA B receptor activation in mouse frontal cortex and hippocampus Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms Trihydrophobin 1 is a new negative regulator of A-Raf kinase MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells.SGK1: The Dark Side of PI3K Signaling.Restoration of PTEN expression alters the sensitivity of prostate cancer cells to EGFR inhibitors.Membrane localization of 3-phosphoinositide-dependent protein kinase-1 stimulates activities of Akt and atypical protein kinase C but does not stimulate glucose transport and glycogen synthesis in 3T3-L1 adipocytes.Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction.AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyve Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD.Positive and negative regulation of Raf kinase activity and function by phosphorylation.Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf.Unique N-region determines low basal activity and limited inducibility of A-RAF kinase: the role of N-region in the evolutionary divergence of RAF kinase function in vertebrates.Cyclic AMP-mediated cyst expansion Normal bone marrow signal-transduction profiles: a requisite for enhanced detection of signaling dysregulations in AML.Akt down-regulates ERK1/2 nuclear localization and angiotensin II-induced cell proliferation through PEA-15.mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON.T-cell receptor signaling enhances transcriptional elongation from latent HIV proviruses by activating P-TEFb through an ERK-dependent pathway.M-Ras induces Ral and JNK activation to regulate MEK/ERK-independent gene expression in MCF-7 breast cancer cells.Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration Exploring G protein-coupled receptor signaling networks using SILAC-based phosphoproteomics Mutation of Y179 on phospholipase D2 (PLD2) upregulates DNA synthesis in a PI3K-and Akt-dependent manner.Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.A novel role for Cdk1/cyclin B in regulating B-raf activation at mitosis AKT upregulates B-Raf Ser445 phosphorylation and ERK1/2 activation in prostate cancer cells in response to androgen depletion.Modulation of the Akt/Ras/Raf/MEK/ERK pathway by A₃ adenosine receptor.

P2860

Q24314807-D777BD21-3D64-4993-8AEE-02BEE2220AE0 Q24316181-B0E9A3AA-C1E7-446A-8C1F-5B36D9D68FB1 Q24537123-527D6E04-BD4A-451E-BE9A-258618D60071 Q24550986-BF445F56-CBBA-4AC8-8034-9CB01BA65450 Q24616946-5BFCE911-617E-4ED4-8086-2A090FD9695E Q24645668-BAD90455-C2D2-42D5-9356-930B44A8090B Q24674150-BD0C61B1-C907-4683-AF21-2CC7759D6AD6 Q26782527-4EC920C2-3BAA-40FB-BD29-FFCDF4F3AB40 Q28202154-381B71AC-15E5-4599-8913-EF892C509063 Q28204417-F7236803-CD37-46D0-AEE1-82A859A7344B Q28235023-B76413CD-CE20-4CA0-9EA0-C473F655400F Q28235129-6CF0106B-AC90-40C6-BF7B-8243D45F1225 Q28580290-98C55A59-40C9-40F5-B407-E5F60B6437E4 Q28585194-537BE480-F052-4108-8C48-6F47764BC315 Q30399129-14416754-27FF-42C5-A773-32CF7162C21E Q30438487-C78E546B-C46D-4C86-9C08-9A89DEB9A38A Q30839834-96E88D85-BF2C-4F4A-B59F-1FC9DBD12E94 Q33668279-2BAB7B8C-7F93-40D6-AC56-D5D2D1ED8DD4 Q33700520-5A347C68-569D-49FB-8F51-338EEEE380C4 Q33808636-79E385EC-87B4-408C-88DD-D07E8A214615 Q33945989-2D643C25-8420-4C8A-ADD8-09409DAE4B59 Q33966221-9C95FBC5-DFE4-40F7-B987-B1855AA15784 Q33967880-2004F4A3-EED0-4F41-8695-143A0350ADE7 Q33987179-94F1E1DA-F502-4085-B97F-235D6DA70645 Q34080535-BEF73254-DF88-4B38-9C97-D658D5EE85FA Q34515800-46E606CE-9B40-4BA6-8823-FC5BC8264C33 Q34646519-6B725149-C205-49F3-B625-22142DD12D29 Q34850793-6A0D256B-0312-447C-A5A0-28C2AD1A5DB1 Q34924495-9D216857-4D4A-49C7-84D2-3EAD5698E4A0 Q35071667-9311923C-4903-4C7D-AA4B-80AD4B6455C4 Q35086777-CE9CF6B0-8160-4060-968E-5F81E4993C53 Q35113716-A3E24B33-FA22-4EFF-8FBB-6B0D5DCFEA81 Q35830796-745412C8-C078-46A3-8495-FE57A06222DF Q36291077-A9B407C8-72FA-4883-8BBB-71D14ED3BB43 Q36418560-0A20B324-BEE9-473B-8A3C-F0D906885EAD Q36512798-1A17492A-0565-46D1-A19D-5EB49B7A0CC6 Q36536571-CCE705CE-C23E-4978-BB72-68E705D94BD1 Q36739904-9919419C-D5C2-42EE-8471-4AF92EE61117 Q36977833-31B6372E-63EF-474B-99E5-044BCC3FFF7E Q37135531-E1247926-AFE4-4D32-9E5B-E52BF4201A0D

P2860

Negative regulation of the serine/threonine kinase B-Raf by Akt

http://www.wikidata.org/entity/Q28139252

description

2000 nî lūn-bûn

@nan

2000 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2000年の論文

@ja

2000年論文

@yue

2000年論文

@zh-hant

2000年論文

@zh-hk

2000年論文

@zh-mo

2000年論文

@zh-tw

2000年论文

@wuu

name

Negative regulation of the serine/threonine kinase B-Raf by Akt

@ast

Negative regulation of the serine/threonine kinase B-Raf by Akt

@en

Negative regulation of the serine/threonine kinase B-Raf by Akt

@nl

type

label

Negative regulation of the serine/threonine kinase B-Raf by Akt

@ast

Negative regulation of the serine/threonine kinase B-Raf by Akt

@en

Negative regulation of the serine/threonine kinase B-Raf by Akt

@nl

prefLabel

Negative regulation of the serine/threonine kinase B-Raf by Akt

@ast

Negative regulation of the serine/threonine kinase B-Raf by Akt

@en

Negative regulation of the serine/threonine kinase B-Raf by Akt

@nl

P1433

Q28139252-F9B81DAE-F3FF-4BEA-9090-F30E4744DB46

P1476

Q28139252-9BF702AB-9959-429E-96C8-AA0FF56513E8

P2093

Q28139252-02ED1251-CCC9-4D62-9C5A-DE940E26D5DE

Q28139252-17994149-0980-443F-A5DA-92B86F9009B7

Q28139252-326930FB-A603-4D5E-A6F3-2595D1AB373D

Q28139252-54E6FC07-F7F5-473F-B5DB-89ECCF72CAEB

Q28139252-70D6A3F3-BDE7-4E2C-A969-E9FA734469E9

Q28139252-AFC2C0EA-F5D7-4BDF-A229-30D5EBF7FF2A

Q28139252-F5FC10FF-FAE8-42EE-AA0A-0FF0F7197675

Q28139252-FD25E610-0DF4-451F-B05E-DDD2C25A2D8C

P304

Q28139252-F3D2C5C1-59F9-4D97-A923-C89CC4B3AAC9

P31

Q28139252-78D14D79-D467-4883-9A1F-31BDD9DA8568

P3181

Q28139252-5D249BB0-DEEC-4A16-8044-72C8A7B5ECC9

P356

Q28139252-C2415241-7842-4B1A-83B8-31F78E008E71

P407

Q28139252-07F5C3AE-8183-4BF2-B8D3-CD44DB1DCF91

P433

Q28139252-F2432D8B-C276-4DCC-AA55-CBEC2485BCE8

P478

Q28139252-E6ED0A92-133C-42AC-AB42-19CB01CACFB9

P577

Q28139252-335F6852-D2B8-4EB6-89D8-46FB0F02601E

Q28139252-B29F2544-FB95-4DD9-B3DF-A0A388D7C611

P698

Q28139252-2C7EAA3F-A929-4B2E-89DD-8D4FFC3A7554

P3181

P356

P1433

Journal of Biological Chemistry

P1476

Negative regulation of the serine/threonine kinase B-Raf by Akt

@en

P2093

A B Vojtek

http://www.w3.org/2001/XMLSchema#string

C Figueroa

http://www.w3.org/2001/XMLSchema#string

J Taylor

http://www.w3.org/2001/XMLSchema#string

K L Guan

http://www.w3.org/2001/XMLSchema#string

K.-L. Guan

http://www.w3.org/2001/XMLSchema#string

T D Barber

http://www.w3.org/2001/XMLSchema#string

T R Brtva

http://www.w3.org/2001/XMLSchema#string

T Zhu

http://www.w3.org/2001/XMLSchema#string

P304

27354-9

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

5033097

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M004371200

http://www.w3.org/2001/XMLSchema#string

P407

P433

35

http://www.w3.org/2001/XMLSchema#string

P478

275

http://www.w3.org/2001/XMLSchema#string

P577

2000-06-26T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

2000-09-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

10869359

http://www.w3.org/2001/XMLSchema#string