Involvement of protein phosphatase 2A in the interleukin-3-stimulated Jak2-Stat5 signaling pathway
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Inhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemiaPhosphoprotein phosphatase-2A docks to Dishevelled and counterregulates Wnt3a/beta-catenin signaling.Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.From the Biology of PP2A to the PADs for Therapy of Hematologic MalignanciesInteraction of STAT6 with its co-activator SRC-1/NCoA-1 is regulated by dephosphorylation of the latter via PP2A.FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia.The PP2A inhibitor SET regulates natural killer cell IFN-gamma production.ReSETting PP2A tumour suppressor activity in blast crisis and imatinib-resistant chronic myelogenous leukaemia.Antagonistic activities of the immunomodulator and PP2A-activating drug FTY720 (Fingolimod, Gilenya) in Jak2-driven hematologic malignanciesPP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells.JAK redux: a second look at the regulation and role of JAKs in the heart.PP2A as a master regulator of the cell cycle.Protein Phosphatase 2A: a Double-Faced Phosphatase of Cellular System and Its Role in Neurodegenerative Disorders.Jak2 inhibition deactivates Lyn kinase through the SET-PP2A-SHP1 pathway, causing apoptosis in drug-resistant cells from chronic myelogenous leukemia patients.Abundance, complexation, and trafficking of Wnt/beta-catenin signaling elements in response to Wnt3a.Inhibition of Src by direct interaction with protein phosphatase 2A.Identification of Shp-2 as a Stat5A phosphatase.PP2A impaired activity is a common event in acute myeloid leukemia and its activation by forskolin has a potent anti-leukemic effect.
P2860
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P2860
Involvement of protein phosphatase 2A in the interleukin-3-stimulated Jak2-Stat5 signaling pathway
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2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@ast
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@en
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@nl
type
label
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@ast
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@en
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@nl
prefLabel
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@ast
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@en
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@nl
P2093
P1476
Involvement of protein phospha ...... d Jak2-Stat5 signaling pathway
@en
P2093
P304
P356
10.1089/107999001750277844
P407
P577
2001-06-01T00:00:00Z