Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
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The Frizzled family: receptors for multiple signal transduction pathwaysArrestins: ubiquitous regulators of cellular signaling pathwaysDirect interaction between NHERF1 and Frizzled regulates β-catenin signalingAssociation of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signalingPhosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase ItchWnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2Radioimmunotherapy of human synovial sarcoma using a monoclonal antibody against FZD10Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/WntWNT5A is a regulator of fibroblast proliferation and resistance to apoptosisA coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteinsCaSR stimulates secretion of Wnt5a from colonic myofibroblasts to stimulate CDX2 and sucrase-isomaltase using Ror2 on intestinal epitheliaWnt/beta-catenin signaling and small molecule inhibitorsWnt signal transduction pathwaysWNT-5A: signaling and functions in health and diseaseThe emerging roles of β-arrestins in fibrotic diseasesKeeping Wnt signalosome in check by vesicular trafficThe role of Ryk and Ror receptor tyrosine kinases in Wnt signal transductionWnt and planar cell polarity signaling in cystic renal diseasemicroRNA regulation of Wnt signaling pathways in development and diseaseThe Integrated Role of Wnt/β-Catenin, N-Glycosylation, and E-Cadherin-Mediated Adhesion in Network Dynamicsβ-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulationStructural Analysis of the Interaction between Dishevelled2 and Clathrin AP-2 Adaptor, A Critical Step in Noncanonical Wnt SignalingARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal MelanomaTiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neuronsPost-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signallingThe sirtuins promote Dishevelled-1 scaffolding of TIAM1, Rac activation and cell migrationPurified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor contextArresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4Wnt5a regulates distinct signalling pathways by binding to Frizzled2All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinasesDishevelled proteins regulate cell adhesion in mouse blastocyst and serve to monitor changes in Wnt signalingPlanar cell polarity signaling: from fly development to human diseasebeta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity.Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cellsInitiation of synapse formation by Wnt-induced MuSK endocytosis.Human embryonic stem cell-derived cardiomyocytes migrate in response to gradients of fibronectin and Wnt5aA disorder-to-order structural transition in the COOH-tail of Fz4 determines misfolding of the L501fsX533-Fz4 mutantIn vivo analysis of formation and endocytosis of the Wnt/β-catenin signaling complex in zebrafish embryosSignaling of human frizzled receptors to the mating pathway in yeast.
P2860
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P2860
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@ast
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@en
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@nl
type
label
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@ast
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@en
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@nl
prefLabel
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@ast
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@en
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@nl
P2093
P3181
P356
P1433
P1476
Dishevelled 2 recruits beta-ar ...... ated endocytosis of Frizzled 4
@en
P2093
Derk ten Berge
Jeff Brown
Larry S Barak
Liaoyuan A Hu
Marc G Caron
Robert J Lefkowitz
Roel Nusse
Seungkirl Ahn
William E Miller
P304
P3181
P356
10.1126/SCIENCE.1082808
P407
P577
2003-09-05T00:00:00Z