Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene
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Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapyIntergenic mRNA molecules resulting from trans-splicingFunctionally defective or altered CYP3A4 and CYP3A5 single nucleotide polymorphisms and their detection with genotyping testsDrug metabolism in human brain: high levels of cytochrome P4503A43 in brain and metabolism of anti-anxiety drug alprazolam to its active metaboliteUp-regulating CYP3A4 expression in C3A cells by transfection with a novel chimeric regulator of hPXR-p53-ADGenetic variability in CYP3A5 and its possible consequences.Screening of Genetic Polymorphisms of CYP3A4 and CYP3A5 Genes.The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors.The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alphaPregnane X receptor and yin yang 1 contribute to the differential tissue expression and induction of CYP3A5 and CYP3A4.Human drug metabolism and the cytochromes P450: application and relevance of in vitro models.The pharmacogenomics of HIV therapy.Genetic variation in CYP3A43 explains racial difference in olanzapine clearance.Drug-metabolizing cytochrome P450s in the brain.Decision tree-based modeling of androgen pathway genes and prostate cancer riskPharmacogenetics of the major polymorphic metabolizing enzymes.The Impact of Gene Polymorphisms on the Success of Anticholinergic Treatment in Children with Overactive Bladder.CYP3A5 phenotype-genotype correlations in a British population.Correlation analysis of gene polymorphisms and β-lactam allergy.Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Polymorphisms of Phase I and Phase II Enzymes and Breast Cancer Risk.Clinical implications of CYP3A polymorphisms.Effects of CYP3A5 genetic polymorphism and smoking on the prognosis of non-small-cell lung cancer.Ethnical disparities of prostate cancer predisposition: genetic polymorphisms in androgen-related genes.Inherent sex-dependent regulation of human hepatic CYP3A5Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans.Constitutional polymorphisms of prostate cancer: prognostic and diagnostic implications.A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine.The Making of a CYP3A Biomarker Panel for Guiding Drug Therapy.Production of human phase 1 and 2 metabolites by whole-cell biotransformation with recombinant microbes.Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function.Developmental changes in the expression and function of cytochrome P450 3A isoforms: evidence from in vitro and in vivo investigations.Cytochrome P450 pharmacogenetics in African populations.Pharmacogenetics of olanzapine metabolism.Genetic variation in CYP3A43 is associated with response to antipsychotic medication.Gene-environment interactions in esophageal cancer.Association between CYP3A5 genotypes with hypertension in Chinese Han population: A case-control study.Molecular basis for prostate cancer racial disparities.
P2860
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P2860
Genomic organization of the human CYP3A locus: identification of a new, inducible CYP3A gene
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@ast
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@en
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@nl
type
label
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@ast
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@en
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@nl
prefLabel
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@ast
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@en
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@nl
P2093
P1476
Genomic organization of the hu ...... of a new, inducible CYP3A gene
@en
P2093
C J Deglmann
D Buntefuss
P304
P356
10.1097/00008571-200103000-00002
P407
P577
2001-03-01T00:00:00Z