Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha
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Acid beta-glucosidase 1 counteracts p38delta-dependent induction of interleukin-6: possible role for ceramide as an anti-inflammatory lipidProtein kinase Cdelta regulates keratinocyte death and survival by regulating activity and subcellular localization of a p38delta-extracellular signal-regulated kinase 1/2 complexApigenin inhibition of involucrin gene expression is associated with a specific reduction in phosphorylation of protein kinase Cdelta Tyr311Differential regulation and properties of MAPKsProteomic profiling of human keratinocytes undergoing UVB-induced alternative differentiation reveals TRIpartite Motif Protein 29 as a survival factorThe potential of p38 MAPK inhibitors to modulate periodontal infections.p38δ regulates p53 to control p21Cip1 expression in human epidermal keratinocytesCorticotropin-releasing hormone inhibits nuclear factor-kappaB pathway in human HaCaT keratinocytes.A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation.Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling.Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.CCAAT/enhancer-binding protein-α suppresses lung tumor development in mice through the p38α MAP kinase pathway.Suppressing AP1 factor signaling in the suprabasal epidermis produces a keratoderma phenotype.PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agentsMultiple PKCdelta tyrosine residues are required for PKCdelta-dependent activation of involucrin expression--a key role of PKCdelta-Y311.Protein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism.Protein arginine methyltransferase 5 (PRMT5) signaling suppresses protein kinase Cδ- and p38δ-dependent signaling and keratinocyte differentiation.Transglutaminase Is Required for Epidermal Squamous Cell Carcinoma Stem Cell Survival.Methylosome Protein 50 and PKCδ/p38δ Protein Signaling Control Keratinocyte Proliferation via Opposing Effects on p21Cip1 Gene ExpressionSulforaphane induction of p21(Cip1) cyclin-dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53-dependent.Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function.Keratinocyte proliferation, differentiation, and apoptosis--differential mechanisms of regulation by curcumin, EGCG and apigenin.Protein kinase C δ increases Kruppel-like factor 4 protein, which drives involucrin gene transcription in differentiating keratinocytes.Synergistic activation of human involucrin gene expression by Fra-1 and p300--evidence for the presence of a multiprotein complex.Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling.Biochemistry of epidermal stem cells.p38δ MAPK: Emerging Roles of a Neglected IsoformMyeloid differentiation factor 88-dependent transcriptional regulation of cyclooxygenase-2 expression by CpG DNA: role of NF-kappaB and p38.Regulation of the human involucrin gene promoter by co-activator proteins.AP1 transcription factors in epidermal differentiation and skin cancerRegulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis.AP1 factor inactivation in the suprabasal epidermis causes increased epidermal hyperproliferation and hyperkeratosis but reduced carcinogen-dependent tumor formationInhibition of apoptosis signal-regulating kinase 1 alters the wound epidermis and enhances auricular cartilage regeneration.MEP50/PRMT5 Reduces Gene Expression by Histone Arginine Methylation and this Is Reversed by PKCδ/p38δ Signaling.Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway.Green tea polyphenol and curcumin inversely regulate human involucrin promoter activity via opposing effects on CCAAT/enhancer-binding protein function.Involvement of p38-mitogen-activated protein kinase in adenosine receptor-mediated relaxation of coronary artery.Protection by pyruvate against glutamate neurotoxicity is mediated by astrocytes through a glutathione-dependent mechanism.Elucidating mechanistic insights into drug action for atopic dermatitis: a systems biology approach.Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes.
P2860
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P2860
Novel protein kinase C isoforms regulate human keratinocyte differentiation by activating a p38 delta mitogen-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@ast
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@en
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@nl
type
label
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@ast
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@en
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@nl
prefLabel
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@ast
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@en
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@nl
P2093
P2860
P356
P1476
Novel protein kinase C isoform ...... enhancer-binding protein alpha
@en
P2093
Anne Deucher
Motoi Ohba
Richard L Eckert
Tatiana Efimova
Toshio Kuroki
P2860
P304
P356
10.1074/JBC.M205098200
P407
P577
2002-08-30T00:00:00Z