A new conceptual framework for enzyme catalysis. Hydrogen tunnelling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes
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Effects of Cavities at the Nicotinamide Binding Site of Liver Alcohol Dehydrogenase on Structure, Dynamics and Catalysisp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptEffects of the donor-acceptor distance and dynamics on hydride tunneling in the dihydrofolate reductase catalyzed reactionChemical Ligation and Isotope Labeling to Locate Dynamic Effects during Catalysis by Dihydrofolate ReductaseThe role of enzyme dynamics and tunnelling in catalysing hydride transfer: studies of distal mutants of dihydrofolate reductase.Effects of a distal mutation on active site chemistry.A computational study of the open and closed forms of the N-lobe human serum transferrin apoprotein.Quantum combinatorial model of gene expression.Quantum delocalization of protons in the hydrogen-bond network of an enzyme active site.Coordinated effects of distal mutations on environmentally coupled tunneling in dihydrofolate reductase.Small temperature dependence of the kinetic isotope effect for the hydride transfer reaction catalyzed by Escherichia coli dihydrofolate reductase.Multidimensional tunneling, recrossing, and the transmission coefficient for enzymatic reactionsHydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems.Evidence for coupled motion and hydrogen tunneling of the reaction catalyzed by glutamate mutase.An analysis of reaction pathways for proton tunnelling in methylamine dehydrogenaseHydrogen-Deuterium Exchange of Lipoxygenase Uncovers a Relationship between Distal, Solvent Exposed Protein Motions and the Thermal Activation Barrier for Catalytic Proton-Coupled Electron Tunneling.Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation.Comparison of enzymatic and non-enzymatic nitroethane anion formation: thermodynamics and contribution of tunneling.Kinetic isotope effects on aromatic and benzylic hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase as probes of chemical mechanism and reactivity.Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase.
P2860
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P2860
A new conceptual framework for enzyme catalysis. Hydrogen tunnelling coupled to enzyme dynamics in flavoprotein and quinoprotein enzymes
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A new conceptual framework for ...... otein and quinoprotein enzymes
@ast
A new conceptual framework for ...... otein and quinoprotein enzymes
@en
A new conceptual framework for ...... otein and quinoprotein enzymes
@nl
type
label
A new conceptual framework for ...... otein and quinoprotein enzymes
@ast
A new conceptual framework for ...... otein and quinoprotein enzymes
@en
A new conceptual framework for ...... otein and quinoprotein enzymes
@nl
prefLabel
A new conceptual framework for ...... otein and quinoprotein enzymes
@ast
A new conceptual framework for ...... otein and quinoprotein enzymes
@en
A new conceptual framework for ...... otein and quinoprotein enzymes
@nl
P1433
P1476
A new conceptual framework for ...... otein and quinoprotein enzymes
@en
P2093
Michael J Sutcliffe
Nigel S Scrutton
P304
P407
P577
2002-07-01T00:00:00Z