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Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategyBiotin-responsive basal ganglia disease maps to 2q36.3 and is due to mutations in SLC19A3Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell linesRestoration of high-level transport activity by human reduced folate carrier/ThTr1 thiamine transporter chimaeras: role of the transmembrane domain 6/7 linker region in reduced folate carrier functionBiotin deficiency reduces expression of SLC19A3, a potential biotin transporter, in leukocytes from human blood.Vitamin B1 (thiamine) uptake by human retinal pigment epithelial (ARPE-19) cells: mechanism and regulationThiamine Deficiency in Tropical Pediatrics: New Insights into a Neglected but Vital Metabolic ChallengeRecent advances in transport of water-soluble vitamins in organs of the digestive system: a focus on the colon and the pancreasBiotin-responsive basal ganglia disease-linked mutations inhibit thiamine transport via hTHTR2: biotin is not a substrate for hTHTR2Novel mutation in the SLC19A2 gene in an African-American female with thiamine-responsive megaloblastic anemia syndromeDifferentiation-dependent up-regulation of intestinal thiamin uptake: cellular and molecular mechanismsCharacterization of the 5'-regulatory region of the human thiamin transporter SLC19A3: in vitro and in vivo studiesThe Concise Guide to PHARMACOLOGY 2013/14: transporters.Intestinal absorption of water-soluble vitamins in health and diseaseEvidence for altered thiamine metabolism in diabetes: Is there a potential to oppose gluco- and lipotoxicity by rational supplementation?A wide spectrum of clinical and brain MRI findings in patients with SLC19A3 mutations.Quantitative analysis and diagnostic significance of methylated SLC19A3 DNA in the plasma of breast and gastric cancer patientsMechanisms of membrane transport of folates into cells and across epithelia.Linking vitamin B1 with cancer cell metabolismFolate and thiamine transporters mediated by facilitative carriers (SLC19A1-3 and SLC46A1) and folate receptors.Thiamine pyrophosphate biosynthesis and transport in the nematode Caenorhabditis elegans.Membrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.Mitochondrial uptake of thiamin pyrophosphate: physiological and cell biological aspects.Association of TM4SF4 with the human thiamine transporter-2 in intestinal epithelial cellsThe physiological role of drug transporters.Regulation of basal promoter activity of the human thiamine pyrophosphate transporter SLC44A4 in human intestinal epithelial cellsMetformin Is a Substrate and Inhibitor of the Human Thiamine Transporter, THTR-2 (SLC19A3).Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes.The molecular identity and characterization of a Proton-coupled Folate Transporter--PCFT; biological ramifications and impact on the activity of pemetrexed.Vitamin transport and homeostasis in mammalian brain: focus on Vitamins B and E.Mechanisms of antifolate resistance and methotrexate efficacy in leukemia cells.Adaptive regulation of human intestinal thiamine uptake by extracellular substrate level: a role for THTR-2 transcriptional regulation.Emerging role of thiamine therapy for prevention and treatment of early-stage diabetic nephropathy.Treatment of genetic defects of thiamine transport and metabolism.Disruption of thiamine uptake and growth of cells by feline leukemia virus subgroup A.Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion.The antitrypanosomal drug melarsoprol competitively inhibits thiamin uptake in mouse neuroblastoma cells.Polarized expression of members of the solute carrier SLC19A gene family of water-soluble multivitamin transporters: implications for physiological function.Cell biology of the human thiamine transporter-1 (hTHTR1). Intracellular trafficking and membrane targeting mechanisms.Sodium-coupled and electrogenic transport of B-complex vitamin nicotinic acid by slc5a8, a member of the Na/glucose co-transporter gene family.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
SLC19A3 encodes a second thiamine transporter ThTr2
@ast
SLC19A3 encodes a second thiamine transporter ThTr2
@en
SLC19A3 encodes a second thiamine transporter ThTr2
@nl
type
label
SLC19A3 encodes a second thiamine transporter ThTr2
@ast
SLC19A3 encodes a second thiamine transporter ThTr2
@en
SLC19A3 encodes a second thiamine transporter ThTr2
@nl
prefLabel
SLC19A3 encodes a second thiamine transporter ThTr2
@ast
SLC19A3 encodes a second thiamine transporter ThTr2
@en
SLC19A3 encodes a second thiamine transporter ThTr2
@nl
P2093
P3181
P1476
SLC19A3 encodes a second thiamine transporter ThTr2
@en
P2093
A Edmondnson
A Rajgopal
I D Goldman
P3181
P356
10.1016/S0925-4439(01)00073-4
P407
P577
2001-11-29T00:00:00Z