Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication
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Identification and characterization of a novel component of the human minichromosome maintenance complexEssential role of phosphorylation of MCM2 by Cdc7/Dbf4 in the initiation of DNA replication in mammalian cellsFunctional cooperation between FACT and MCM helicase facilitates initiation of chromatin DNA replicationCharacterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6Human Mcm proteins at a replication origin during the G1 to S phase transitionMCM-BP regulates unloading of the MCM2-7 helicase in late S phaseA double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replicationPreventing re-replication of chromosomal DNA.The Croonian Lecture 2001 hunting the antisocial cancer cell: MCM proteins and their exploitationHuman Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replicationMechanisms for initiating cellular DNA replicationThe Mcm2-7 replicative helicase: a promising chemotherapeutic targetThe minichromosome maintenance replicative helicaseA dominantly acting murine allele of Mcm4 causes chromosomal abnormalities and promotes tumorigenesisA conserved MCM single-stranded DNA binding element is essential for replication initiationTwo mcm3 mutations affect different steps in the initiation of DNA replication.Differences in the single-stranded DNA binding activities of MCM2-7 and MCM467: MCM2 and MCM5 define a slow ATP-dependent step.Reconstitution of the Mcm2-7p heterohexamer, subunit arrangement, and ATP site architecture.Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex.Roles of Mcm7 and Mcm4 subunits in the DNA helicase activity of the mouse Mcm4/6/7 complexTwo heads are better than one: regulation of DNA replication by hexameric helicasesDbf4-Cdc7 phosphorylation of Mcm2 is required for cell growth.Hexameric ring structure of the full-length archaeal MCM protein complex.ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryoteStructural and mechanistic insights into Mcm2-7 double-hexamer assembly and functionDe novo assembly of genuine replication forks on an immobilized circular plasmid in Xenopus egg extracts.Differential requirements for MCM proteins in DNA replication in Drosophila S2 cellsEukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.The effects of oligomerization on Saccharomyces cerevisiae Mcm4/6/7 functionDynamics of pre-replicative complex assembly.Functional cooperation between FACT and MCM is coordinated with cell cycle and differential complex formation.Interaction of the S-phase cyclin Clb5 with an "RXL" docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch.Phosphorylation of Mcm2 modulates Mcm2-7 activity and affects the cell's response to DNA damageStructural insights into the Cdt1-mediated MCM2-7 chromatin loading.The Saccharomyces cerevisiae Mcm6/2 and Mcm5/3 ATPase active sites contribute to the function of the putative Mcm2-7 'gate'.A novel zinc finger is required for Mcm10 homocomplex assembly.A rotary pumping model for helicase function of MCM proteins at a distance from replication forks.The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding.Control of DNA replication licensing in a cell cycle.Cdc7 kinase complex: a key regulator in the initiation of DNA replication.
P2860
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P2860
Interactions between two catalytically distinct MCM subgroups are essential for coordinated ATP hydrolysis and DNA replication
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Interactions between two catal ...... hydrolysis and DNA replication
@ast
Interactions between two catal ...... hydrolysis and DNA replication
@en
Interactions between two catal ...... hydrolysis and DNA replication
@nl
type
label
Interactions between two catal ...... hydrolysis and DNA replication
@ast
Interactions between two catal ...... hydrolysis and DNA replication
@en
Interactions between two catal ...... hydrolysis and DNA replication
@nl
prefLabel
Interactions between two catal ...... hydrolysis and DNA replication
@ast
Interactions between two catal ...... hydrolysis and DNA replication
@en
Interactions between two catal ...... hydrolysis and DNA replication
@nl
P3181
P1433
P1476
Interactions between two catal ...... hydrolysis and DNA replication
@en
P2093
A Schwacha
P304
P3181
P356
10.1016/S1097-2765(01)00389-6
P407
P577
2001-11-01T00:00:00Z