Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function
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The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoformsEndogenous G protein-coupled receptor kinase 6 Regulates M3 muscarinic acetylcholine receptor phosphorylation and desensitization in human SH-SY5Y neuroblastoma cellsAnalysis of ligand-stimulated CC chemokine receptor 5 (CCR5) phosphorylation in intact cells using phosphosite-specific antibodiesPhosphorylation by casein kinase 2 induces PACS-1 binding of nephrocystin and targeting to cilia.KISS1R intracellular trafficking and degradation: effect of the Arg386Pro disease-associated mutation.G-protein-coupled receptor phosphorylation: where, when and by whom.Kinin-stimulated B1 receptor signaling depends on receptor endocytosis whereas B2 receptor signaling does not.Mechanisms regulating the expression, self-maintenance, and signaling-function of the bradykinin B2 and B1 receptors.Structure and signalling pathways of kinin receptors.Positive cooperativity between the thrombin and bradykinin B2 receptors enhances arachidonic acid release.Phosphorylation and regulation of a G protein-coupled receptor by protein kinase CK2.Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences.Location, location, location...site-specific GPCR phosphorylation offers a mechanism for cell-type-specific signalling.New topics in bradykinin research.The enhanced permeability retention effect: a new paradigm for drug targeting in infection.Helix 8 plays a crucial role in bradykinin B(2) receptor trafficking and signaling.Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia.The C-terminal tail of CRTH2 is a key molecular determinant that constrains Galphai and downstream signaling cascade activation.C-terminal fusion of eGFP to the bradykinin B2 receptor strongly affects down-regulation but not receptor internalization or signaling.3'-Untranslated region of the type 2 bradykinin receptor is a potent regulator of gene expression.Mutation of tyrosine in the conserved NPXXY sequence leads to constitutive phosphorylation and internalization, but not signaling, of the human B2 bradykinin receptor.Wortmannin alters the intracellular trafficking of the bradykinin B2 receptor: role of phosphoinositide 3-kinase and Rab5.Neutrophils and the kallikrein-kinin system in proteinase-activated receptor 4-mediated inflammation in rodents.The kallikrein-kinin system in experimental Chagas disease: a paradigm to investigate the impact of inflammatory edema on GPCR-mediated pathways of host cell invasion by Trypanosoma cruzi.A different molecular interaction of bradykinin and the synthetic agonist FR190997 with the human B2 receptor: evidence from mutational analysis.Changes in amino-terminal portion of human B2 receptor selectively increase efficacy of synthetic ligand HOE 140 but not of cognate ligand bradykinin.Implication of the Kallikrein-Kinin system in neurological disorders: Quest for potential biomarkers and mechanisms.Phosphorylation of the endogenous thyrotropin-releasing hormone receptor in pituitary GH3 cells and pituitary tissue revealed by phosphosite-specific antibodies.G Protein-Coupled Receptor Kinase 3 and Protein Kinase C Phosphorylate the Distal C-Terminal Tail of the Chemokine Receptor CXCR4 and Mediate Recruitment of β-Arrestin.
P2860
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P2860
Determination of bradykinin B2 receptor in vivo phosphorylation sites and their role in receptor function
description
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im November 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 2 November 2001)
@en
vedecký článok (publikovaný 2001/11/02)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/11/02)
@nl
наукова стаття, опублікована в листопаді 2001
@uk
name
Determination of bradykinin B2 ...... heir role in receptor function
@ast
Determination of bradykinin B2 ...... heir role in receptor function
@en
Determination of bradykinin B2 ...... heir role in receptor function
@nl
type
label
Determination of bradykinin B2 ...... heir role in receptor function
@ast
Determination of bradykinin B2 ...... heir role in receptor function
@en
Determination of bradykinin B2 ...... heir role in receptor function
@nl
prefLabel
Determination of bradykinin B2 ...... heir role in receptor function
@ast
Determination of bradykinin B2 ...... heir role in receptor function
@en
Determination of bradykinin B2 ...... heir role in receptor function
@nl
P2093
P2860
P50
P356
P1476
Determination of bradykinin B2 ...... heir role in receptor function
@en
P2093
C Wernstedt
F Alhenc-Gelas
P2860
P304
P356
10.1074/JBC.M107024200
P407
P577
2001-11-02T00:00:00Z