Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators - Wikidata - awgldk - TriplyDB

Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators

Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators

http://www.wikidata.org/entity/Q28214436

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Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus Coactivator recruitment of AhR/ARNT1 Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions A model for aryl hydrocarbon receptor-activated gene expression shows potency and efficacy changes and predicts squelching due to competition for transcription co-activators Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice.A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses.Estrogen modulates transactivations of SXR-mediated liver X receptor response element and CAR-mediated phenobarbital response element in HepG2 cells Small-molecule modulators of the constitutive androstane receptor.Nuclear receptors CAR and PXR in the regulation of hepatic metabolism.CAR and PXR: the xenobiotic-sensing receptors.Bioinformatic analysis of microRNA networks following the activation of the constitutive androstane receptor (CAR) in mouse liver Estradiol induces cytochrome P450 2B6 expression at high concentrations: implication in estrogen-mediated gene regulation in pregnancy.Deciphering the roles of the constitutive androstane receptor in energy metabolism.Corepressors of agonist-bound nuclear receptors Regulation of hepatic phase II metabolism in pregnant mice PXR and CAR: nuclear receptors which play a pivotal role in drug disposition and chemical toxicity.The pregnane X receptor down-regulates organic cation transporter 1 (SLC22A1) in human hepatocytes by competing for ("squelching") SRC-1 coactivator Species-specific regulation of PXR/CAR/ER-target genes in the mouse and rat liver elicited by o, p'-DDT Role of the constitutive androstane receptor in obesity and type 2 diabetes: a case study of the endobiotic function of a xenobiotic receptor.Estrogenic endocrine-disrupting chemicals: molecular mechanisms of actions on putative human diseases.Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha. Functional implications in hepatic cholesterol and glucose metabolism.Role of an mSin3A-Swi/Snf chromatin remodeling complex in the feedback repression of bile acid biosynthesis by SHP.Structural determinants of constitutive androstane receptor required for its glucocorticoid receptor interacting protein-1-mediated nuclear accumulation.Characterization of sea bass FSHβ 5' flanking region: transcriptional control by 17β-estradiol.CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.Regulation of Msx2 gene expression by steroid hormones in human nonmalignant and malignant breast cancer explants cultured in vitro.Functional inhibitory cross-talk between constitutive androstane receptor and hepatic nuclear factor-4 in hepatic lipid/glucose metabolism is mediated by competition for binding to the DR1 motif and to the common coactivators, GRIP-1 and PGC-1alpha.A Cell-Permeable Stapled Peptide Inhibitor of the Estrogen Receptor/Coactivator Interaction.In vivo deletion of CAR resulted in high bone mass phenotypes in male mice.

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Inhibitory cross-talk between estrogen receptor (ER) and constitutively activated androstane receptor (CAR). CAR inhibits ER-mediated signaling pathway by squelching p160 coactivators

http://www.wikidata.org/entity/Q28214436

description

2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 2002

@ast

im September 2002 veröffentlichter wissenschaftlicher Artikel

@de

scientific article (publication date: 13 September 2002)

@en

vedecký článok (publikovaný 2002/09/13)

@sk

vědecký článek publikovaný v roce 2002

@cs

wetenschappelijk artikel (gepubliceerd op 2002/09/13)

@nl

наукова стаття, опублікована у вересні 2002

@uk

name

Inhibitory cross-talk between ...... y squelching p160 coactivators

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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type

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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prefLabel

Inhibitory cross-talk between ...... y squelching p160 coactivators

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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Journal of Biological Chemistry

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Inhibitory cross-talk between ...... y squelching p160 coactivators

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P2093

Gyesik Min

http://www.w3.org/2001/XMLSchema#string

Hwajin Kim

http://www.w3.org/2001/XMLSchema#string

Jongsook Kim Kemper

http://www.w3.org/2001/XMLSchema#string

Larry Petz

http://www.w3.org/2001/XMLSchema#string

Yangjin Bae

http://www.w3.org/2001/XMLSchema#string

P2860

Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta

A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements

The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

Estrogen receptor transcription and transactivation: Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer.

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

The steroid and thyroid hormone receptor superfamily

Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR

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34626-33

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scholarly article

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10.1074/JBC.M205239200

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37

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277

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2002-09-13T00:00:00Z

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12114525

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