Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
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PIAS1 interacts with FLASH and enhances its co-activation of c-MybModification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcriptionModification with SUMO. A role in transcriptional regulationTranscription factor Sp3 is silenced through SUMO modification by PIAS1PIAS-1 is a checkpoint regulator which affects exit from G1 and G2 by sumoylation of p73The novel PIAS-like protein hZimp10 is a transcriptional co-activator of the p53 tumor suppressorThe genetics of the p53 pathway, apoptosis and cancer therapy.PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcriptionRegulation of gene-activation pathways by PIAS proteins in the immune systemPIAS1 activates the expression of smooth muscle cell differentiation marker genes by interacting with serum response factor and class I basic helix-loop-helix proteins.The PIAS-like protein Zimp10 is essential for embryonic viability and proper vascular developmentProtein inhibitor of activated STAT1 interacts with and up-regulates activities of the pro-proliferative transcription factor Krüppel-like factor 5.Differential regulation of the two transcriptional activation domains of the coiled-coil coactivator CoCoA by sumoylation.Negative regulation of NF-kappaB signaling by PIAS1.A novel role for protein inhibitor of activated STAT (PIAS) proteins in modulating the activity of Zimp7, a novel PIAS-like protein, in androgen receptor-mediated transcriptionPhosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1.Emerging roles of SUMO modification in arthritis.A single-nucleotide variation in a p53-binding site affects nutrient-sensitive human SIRT1 expressionZNF76, a novel transcriptional repressor targeting TATA-binding protein, is modulated by sumoylation.Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net.The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity.Ubiquitin and ubiquitin-like modifications of the p53 family.Roles and regulation of stat family transcription factors in human breast cancer.PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleusPML nuclear bodies and apoptosis.The Expression of miR-375 Is Associated with Carcinogenesis in Three Subtypes of Lung CancerSTAT1 modification improves therapeutic effects of interferons on lung cancer cellsThe SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci.Coping with stress: multiple ways to activate p53.Ribozyme-mediated targeting of IkappaBgamma inhibits melanoma invasion and metastasis.Identification of a novel role of ZMIZ2 protein in regulating the activity of the Wnt/β-catenin signaling pathway.Egr1 promotes growth and survival of prostate cancer cells. Identification of novel Egr1 target genes.PIAS1-modulated Smad2/4 complex activation is involved in zinc-induced cancer cell apoptosis.PIASx acts as an Elk-1 coactivator by facilitating derepression.SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence.A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation.Modification of Drosophila p53 by SUMO modulates its transactivation and pro-apoptotic functions.Statin-mediated correction of STAT1 signaling and inducible nitric oxide synthase expression in cystic fibrosis epithelial cells.Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3beta in prostate cancer cells.PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity.
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Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
description
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im März 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 8 March 2002)
@en
vedecký článok (publikovaný 2002/03/08)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/03/08)
@nl
наукова стаття, опублікована в березні 2002
@uk
name
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@ast
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@en
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@nl
type
label
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@ast
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@en
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@nl
prefLabel
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@ast
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@en
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@nl
P2093
P2860
P356
P1476
Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)
@en
P2093
C Wilson Xu
Juliana H Xu
Tamar Megidish
P2860
P304
P356
10.1074/JBC.C200001200
P407
P577
2002-03-08T00:00:00Z