Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon
about
sameAs
Specificity in Ras and Rap signalingThe M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytesPhosphoinositides: tiny lipids with giant impact on cell regulationFilamin and phospholipase C-ε are required for calcium signaling in the Caenorhabditis elegans spermathecaPhospholipase cε, an effector of ras and rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma.Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?G-protein-coupled receptor agonists activate endogenous phospholipase Cepsilon and phospholipase Cbeta3 in a temporally distinct mannerTanshinone IIA prevented brain iron dyshomeostasis in cerebral ischemic ratsCongenital semilunar valvulogenesis defect in mice deficient in phospholipase C epsilon.Human RAS superfamily proteins and related GTPases.Direct activation of phospholipase C-epsilon by Rho.Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.PLCε mediated sustained signaling pathways.Role of phospholipase Cε in physiological phosphoinositide signaling networks.Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferationG-protein signaling: back to the futurePhospholipase Cε Modulates Rap1 Activity and the Endothelial Barrier.Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase CϵActivity of PLCε contributes to chemotaxis of fibroblasts towards PDGFPhospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses.Structure, functional regulation and signaling properties of Rap2B.Rap2B promotes migration and invasion of human suprarenal epithelioma.A sequence variant in the phospholipase C epsilon C2 domain is associated with esophageal carcinoma and esophagitis.The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression.U-73122 reduces the cell growth in cultured MG-63 ostesarcoma cell line involving Phosphoinositide-specific Phospholipases C.Siah proteins induce the epidermal growth factor-dependent degradation of phospholipase Cepsilon.Phospholipase C-epsilon augments epidermal growth factor-dependent cell growth by inhibiting epidermal growth factor receptor down-regulation.Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors.Rap2B-dependent stimulation of phospholipase C-epsilon by epidermal growth factor receptor mediated by c-Src phosphorylation of RasGRP3.Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins.Filamin and Phospholipase C-ε are required for calcium signaling in the Caenorhabditis elegans Spermatheca.p53 upregulates PLCε-IP3-Ca2+ pathway and inhibits autophagy through its target gene Rap2B.Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in β-cells of phospholipase C-ε knockout mice.Phospholipase C isozymes as effectors of Ras superfamily GTPases.Identification of a novel domain of Ras and Rap1 that directs their differential subcellular localizations.Enhanced activation of Akt and extracellular-regulated kinase pathways by simultaneous occupancy of Gq-coupled 5-HT2A receptors and Gs-coupled 5-HT7A receptors in PC12 cells.β-Cell signalling and insulin secretagogues: A path for improved diabetes therapy.Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis.Neuronal lineage-specific induction of phospholipase Cepsilon expression in the developing mouse brain.Mechanistic regulation of epithelial-to-mesenchymal transition through RAS signaling pathway and therapeutic implications in human cancer.
P2860
Q24657954-6A747EBC-FECD-440F-9AE8-376274749AFCQ24679529-E4951C05-2B7F-4FDD-8BBA-5318C01D7406Q27012953-49FAFB6D-3252-4359-AFF8-4134A8F5CB38Q27322806-3977C19F-D0CC-4C97-B4A2-E4A11EAC0090Q27345107-20D55505-0D16-49A0-8FBC-B7AA260ADEECQ27690752-B29AE7C0-8B5F-4795-9009-3CFAB8950355Q28564687-84DD442D-2C4D-40E1-9919-3205FCFFE006Q28579242-F53B2D1A-8FD8-47DB-9990-54BB5261B729Q30475786-6CD69C0C-F632-4911-8044-55C48AC7B34DQ33689727-836C65AD-F0D8-4EC5-B2E9-A6020C3CBB32Q34219906-385A1E39-915C-4C6E-A8E4-9E9EC32E1E41Q34436421-04A803CA-9173-475E-8407-5383092B0B44Q35038894-2269BC20-0999-4476-BE63-B77264DB17FCQ35887430-4622A5E3-0862-459A-AA13-EB9FB4111989Q36024090-E8A42C77-F398-46CA-B4B6-B940D943B516Q36061579-C14360AB-9CC4-4F58-83D2-DEEA913C43CCQ36128605-E5C2D827-BF8E-4190-A63A-CC4428B2FFFFQ36283751-E5ADF474-EB4C-4111-A898-D40B9A0CA93DQ36619468-9FE86211-5624-4575-AB7B-4C963A881D64Q36653811-D42FF4A6-BB79-474B-A95B-AEC423565B1BQ36741049-CEB359FC-9083-41C4-810D-55592E38820AQ36833076-D8974BC9-A299-4E0C-99A7-F0FABD38E8D2Q37597313-AF7266C9-F5E2-4EC0-A4B2-DA07E6A6EB10Q37738063-AB7925D2-6CC6-4BF5-8E24-82AA1F848469Q38619801-9CAB90E1-A41C-4DB3-8E36-776861A53631Q40052982-65148F4D-2C96-4F2F-8FDF-CDEB82FEC7F8Q40063467-9EF02849-A96F-467E-9C83-E48278B35468Q40524023-C625EDA7-3440-46AD-99F8-4E3CEC4F481EQ40886547-D6FE3B67-AE9A-4AB7-9B63-5B8FF86AC614Q41849600-1429F960-25E5-4C7F-B813-F22B3BCF854BQ41886104-64A26BFB-351E-4FF9-8A8A-B0BB37A320B7Q42371457-60A17E1A-9945-4178-946E-78B5CEA3B6B9Q42839735-A6D8CCE3-BD33-453E-95D8-8695802BE9DCQ43138796-D10E427C-8CE0-4838-9BD4-8AF2193AA161Q44805571-0113D5D2-9F41-4188-B9E9-802DEF247DB7Q45192487-96B97DD4-78F6-41E2-8E6B-C4A780DAB950Q47843111-2CA67BC4-6F75-4B00-89A2-31B50833D0F9Q47882828-51EB86FD-3BBF-4FAE-8436-48DDDBB1BA96Q48307745-401099E1-0555-486C-BFA4-D09D66CE1200Q50057521-354C123C-9ED6-466F-AC60-B42FEB25537D
P2860
Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Differential roles of Ras and ...... ion of phospholipase C epsilon
@ast
Differential roles of Ras and ...... ion of phospholipase C epsilon
@en
Differential roles of Ras and ...... ion of phospholipase C epsilon
@nl
type
label
Differential roles of Ras and ...... ion of phospholipase C epsilon
@ast
Differential roles of Ras and ...... ion of phospholipase C epsilon
@en
Differential roles of Ras and ...... ion of phospholipase C epsilon
@nl
prefLabel
Differential roles of Ras and ...... ion of phospholipase C epsilon
@ast
Differential roles of Ras and ...... ion of phospholipase C epsilon
@en
Differential roles of Ras and ...... ion of phospholipase C epsilon
@nl
P2093
P3181
P356
P1433
P1476
Differential roles of Ras and ...... ion of phospholipase C epsilon
@en
P2093
Chunhua Song
Dongmei Wu
Hironori Edamatsu
Makoto Tadano
Takaya Satoh
Tohru Kataoka
Xianlong Gao
P2888
P304
P3181
P356
10.1038/SJ.ONC.1206003
P407
P577
2002-11-21T00:00:00Z
P5875
P6179
1004812230