Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy
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Paired-type homeodomain transcription factors are imported into the nucleus by karyopherin 13A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARXFunctional analysis of transcriptional repressor Otx3/Dmbx1The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genesCooperative activation of Xenopus rhodopsin transcription by paired-like transcription factorsThe orphan nuclear hormone receptor ERRbeta controls rod photoreceptor survival.Enhanced protein domain discovery by using language modeling techniques from speech recognition.Barrier to autointegration factor interacts with the cone-rod homeobox and represses its transactivation function.FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo.Mutation discovered in a feline model of human congenital retinal blinding disease.Two novel CRX mutant proteins causing autosomal dominant Leber congenital amaurosis interact differently with NRL.Mechanisms of blindness: animal models provide insight into distinct CRX-associated retinopathiesRNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse modelThe domestic cat as a large animal model for characterization of disease and therapeutic intervention in hereditary retinal blindness.Mechanistically distinct mouse models for CRX-associated retinopathy.Next-generation genetic testing for retinitis pigmentosa.Crx activates opsin transcription by recruiting HAT-containing co-activators and promoting histone acetylation.Regulation of photoreceptor gene expression by Crx-associated transcription factor networkCell autonomous and nonautonomous requirements for Delltalike1 during early mouse retinal neurogenesis.CrxRdy Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis.Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina.OTX2 loss causes rod differentiation defect in CRX-associated congenital blindness.Cell Type-Specific Epigenomic Analysis Reveals a Uniquely Closed Chromatin Architecture in Mouse Rod Photoreceptors.A specific box switches the cell fate determining activity of XOTX2 and XOTX5b in the Xenopus retina.Molecular analysis of a human PAX6 homeobox mutant.Chromatin immunoprecipitation identifies photoreceptor transcription factor targets in mouse models of retinal degeneration: new findings and challenges.Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx.Panel-Based Population Next-Generation Sequencing for Inherited Retinal DegenerationsCrx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 MiceOTX2 and CRX rescue overlapping and photoreceptor-specific functions in the Drosophila eyeGenetic screening of LCA in Belgium: predominance of CEP290 and identification of potential modifier alleles in AHI1 of CEP290-related phenotypesDetection of novel genetic variation in autosomal dominant retinitis pigmentosa.Prescreening whole exome sequencing results from patients with retinal degeneration for variants in genes associated with retinal degeneration.CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites
P2860
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P2860
Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@ast
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@en
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@nl
type
label
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@ast
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@en
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@nl
prefLabel
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@ast
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@en
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@nl
P2093
P3181
P356
P1476
Functional analysis of cone-ro ...... ociated with retinal dystrophy
@en
P2093
Donald J Zack
Qing-Liang Wang
Shiming Chen
Yufang Wang
P304
P3181
P356
10.1093/HMG/11.8.873
P407
P577
2002-04-15T00:00:00Z