Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

P2860

Q57172050-D8A6F003-C7D7-4B02-A762-10D1DA6B119D Q58793924-9EC130B3-873E-4536-9A38-16B7BB36C629

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Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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http://www.wikidata.org/entity/Q41147717

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2017 nî lūn-bûn

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2017年の論文

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2017年論文

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2017年論文

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2017年論文

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Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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prefLabel

Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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P1476

Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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Anne K Hennig

http://www.w3.org/2001/XMLSchema#string

Courtney D Linne

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Philip A Ruzycki

http://www.w3.org/2001/XMLSchema#string

Shiming Chen

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P2860

Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor

A range of clinical phenotypes associated with mutations in CRX, a photoreceptor transcription-factor gene.

Visual improvement in Leber congenital amaurosis and the CRX genotype

Functional analysis of cone-rod homeobox (CRX) mutations associated with retinal dystrophy

Mutations in the cone-rod homeobox gene are associated with the cone-rod dystrophy photoreceptor degeneration

Mouse model resources for vision research.

Functional domains of the cone-rod homeobox (CRX) transcription factor.

Two novel CRX mutant proteins causing autosomal dominant Leber congenital amaurosis interact differently with NRL.

Mechanisms of blindness: animal models provide insight into distinct CRX-associated retinopathies

Dominant Leber congenital amaurosis, cone-rod degeneration, and retinitis pigmentosa caused by mutant versions of the transcription factor CRX.

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4644-4653

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scholarly article

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10.1167/IOVS.17-22075

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English

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P478

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2017-09-01T00:00:00Z

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P698

28903150

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P921

Photoreceptor protein

P932

5597032

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Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

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P2860

P2860

Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P921

P932