The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
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Inclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formationTargeting and activation of Rac1 are mediated by the exchange factor beta-Pix.Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/betaPIX signaling complex.Bi-modal regulation of a formin by srGAP2A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domainsCortactin signalling and dynamic actin networksLoss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesisUnder lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesThe development of a novel high throughput computational tool for studying individual and collective cellular migrationAPP intracellular domain-WAVE1 pathway reduces amyloid-β production.PRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating ProteinAbi1 is essential for the formation and activation of a WAVE2 signalling complexExpression and subcellular localization of WAVE isoforms in the megakaryocyte/platelet lineagePeptide array X-linking (PAX): a new peptide-protein identification approachThe inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cellsWAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motilityIdentification and characterization of a G-protein regulatory motif in WAVE1ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memoryAKAP signalling complexes: focal points in space and timeF-BAR family proteins, emerging regulators for cell membrane dynamic changes-from structure to human diseases.The BAR Domain Superfamily Proteins from Subcellular Structures to Human DiseasesSH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexesF-BAR domain proteins: Families and function.Physical mechanisms of signal integration by WASP family proteins.The proposed functions of membrane curvatures mediated by the BAR domain superfamily proteins.Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalitiesSCAR knockouts in Dictyostelium: WASP assumes SCAR's position and upstream regulators in pseudopodsThe F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently.A WAVE-1 and WRP signaling complex regulates spine density, synaptic plasticity, and memory.srGAP1 regulates lamellipodial dynamics and cell migratory behavior by modulating Rac1 activity.Vascular endothelial growth factor causes translocation of p47phox to membrane ruffles through WAVE1.Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.The F-BAR domain of SRGP-1 facilitates cell-cell adhesion during C. elegans morphogenesisRegulation of the postsynaptic cytoskeleton: roles in development, plasticity, and disorders.Anchored protein kinase A recruitment of active Rac GTPase.Sequestering Rac with PKA confers cAMP control of cytoskeletal remodeling.The role of Rho GTPase proteins in CNS neuronal migration.
P2860
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P2860
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@ast
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@en
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@nl
type
label
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@ast
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@en
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@nl
prefLabel
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@ast
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@en
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@nl
P2093
P3181
P356
P1433
P1476
The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling
@en
P2093
Gary A Wayman
John D Scott
Kathleen L Binns
Scott H Soderling
Siew Hwa Ong
Stephen M Davee
P2888
P3181
P356
10.1038/NCB886
P407
P577
2002-12-01T00:00:00Z
P5875
P6179
1025769793