Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle
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The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancersPeptide microarray analysis of substrate specificity of the transmembrane Ser/Thr kinase KPI-2 reveals reactivity with cystic fibrosis transmembrane conductance regulator and phosphorylaseDepletion of IK causes mitotic arrest through aberrant regulation of mitotic kinases and phosphatasesPhosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-AThe decision to enter mitosis: feedback and redundancy in the mitotic entry networkA cancer-associated aurora A mutant is mislocalized and misregulated due to loss of interaction with TPX2SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1.Identification of genes involved in Ca2+ ionophore A23187-mediated apoptosis and demonstration of a high susceptibility for transcriptional repression of cell cycle genes in B lymphoblasts from a patient with Scott syndromeHeading off with the herd: how cancer cells might maneuver supernumerary centrosomes for directional migrationProtein phosphatase-1 binding to scd5p is important for regulation of actin organization and endocytosis in yeast.Aurora-A kinase maintains the fidelity of early and late mitotic events in HeLa cellsBRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transitionRegulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translationThe cellular geography of aurora kinasesActivation of Aurora-A kinase by protein phosphatase inhibitor-2, a bifunctional signaling proteinMLN8054, a small-molecule inhibitor of Aurora A, causes spindle pole and chromosome congression defects leading to aneuploidy.Dietary flavonoid fisetin induces a forced exit from mitosis by targeting the mitotic spindle checkpointsiRNA-mediated gene silencing: a global genome view.Evidence toward a dual phosphatase mechanism that restricts Aurora A (Thr-295) phosphorylation during the early embryonic cell cycle.Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases.VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo.The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.Identification of phosphorylated residues that affect the activity of the mitotic kinase Aurora-A.Centrosome amplification and the development of cancer.Control of the centriole and centrosome cycles by ubiquitination enzymes.Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion.Issues in interpreting the in vivo activity of Aurora-AFunction and regulation of Aurora/Ipl1p kinase family in cell division.Polar expeditions--provisioning the centrosome for mitosis.Aurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.Aurora kinase A controls meiosis I progression in mouse oocytes.KIBRA protein phosphorylation is regulated by mitotic kinase aurora and protein phosphatase 1.Kinome-wide siRNA screening identifies molecular targets mediating the sensitivity of pancreatic cancer cells to Aurora kinase inhibitorsFunctional interaction of Aurora-A and PP2A during mitosisAurora-A - a guardian of poles.Aurora A and B kinases as targets for cancer: will they be selective for tumors?Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells.
P2860
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P2860
Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Interaction and feedback regul ...... gh mitotic cell division cycle
@ast
Interaction and feedback regul ...... gh mitotic cell division cycle
@en
Interaction and feedback regul ...... gh mitotic cell division cycle
@nl
type
label
Interaction and feedback regul ...... gh mitotic cell division cycle
@ast
Interaction and feedback regul ...... gh mitotic cell division cycle
@en
Interaction and feedback regul ...... gh mitotic cell division cycle
@nl
prefLabel
Interaction and feedback regul ...... gh mitotic cell division cycle
@ast
Interaction and feedback regul ...... gh mitotic cell division cycle
@en
Interaction and feedback regul ...... gh mitotic cell division cycle
@nl
P2093
P2860
P356
P1476
Interaction and feedback regul ...... gh mitotic cell division cycle
@en
P2093
P2860
P304
P356
10.1074/JBC.M107540200
P407
P577
2001-12-07T00:00:00Z