BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition - Wikidata - awgldk - TriplyDB

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

http://www.wikidata.org/entity/Q28247388

about

Drugging MYCN through an allosteric transition in Aurora kinase A ATM activation by ionizing radiation requires BRCA1-associated BAAT1 Aurora kinase-A inactivates DNA damage-induced apoptosis and spindle assembly checkpoint response functions of p73 The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution Aurora-A Kinase as a Promising Therapeutic Target in Cancer Aurora Kinases and Potential Medical Applications of Aurora Kinase Inhibitors: A Review Aurora kinase A in gastrointestinal cancers: time to target Aurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients.Is there more to BARD1 than BRCA1?Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155 Aurora-A interacts with AP-2α and down regulates its transcription activity Aurora kinases: novel therapy targets in cancers The negative interplay between Aurora A/B and BRCA1/2 controls cancer cell growth and tumorigenesis via distinct regulation of cell cycle progression, cytokinesis, and tetraploidy Aurora kinase inhibitors--rising stars in cancer therapeutics?Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.Aurora kinase A promotes ovarian tumorigenesis through dysregulation of the cell cycle and suppression of BRCA2.Danusertib, an aurora kinase inhibitor.Kaposi's sarcoma herpesvirus upregulates Aurora A expression to promote p53 phosphorylation and ubiquitylation Expression of aurora kinase A is associated with metastasis-free survival in node-negative breast cancer patients.Missense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.Efficient prediction of human protein-protein interactions at a global scale.Issues in interpreting the in vivo activity of Aurora-A AURKA and BRCA2 expression highly correlate with prognosis of endometrioid ovarian carcinoma.Increased expression of tumor proliferation genes in Hispanic women with early-stage breast cancer MUC16 induced rapid G2/M transition via interactions with JAK2 for increased proliferation and anti-apoptosis in breast cancer cells Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase.Role of BRCA1 in controlling mitotic arrest in ovarian cystadenoma cells.Aurora kinase inhibitors as anticancer molecules.Estrogen-induced aurora kinase-A (AURKA) gene expression is activated by GATA-3 in estrogen receptor-positive breast cancer cells.Phosphatidylinositol 3-kinase/Akt signaling enhances nuclear localization and transcriptional activity of BRCA1 Expression of oncogenic BARD1 isoforms affects colon cancer progression and correlates with clinical outcome.Aurora kinases: shining lights on the therapeutic horizon?Deregulation of BRCA1 leads to impaired spatiotemporal dynamics of γ-H2AX and DNA damage responses in Huntington's disease Aurora kinase inhibitor VE 465 synergistically enhances cytotoxicity of carboplatin in ovarian cancer cells through induction of apoptosis and downregulation of histone 3 Aurora A and B kinases as targets for cancer: will they be selective for tumors?Enhancement of radiation response by inhibition of Aurora-A kinase using siRNA or a selective Aurora kinase inhibitor PHA680632 in p53-deficient cancer cells

P2860

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P2860

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

http://www.wikidata.org/entity/Q28247388

description

2004 nî lūn-bûn

@nan

2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2004年の論文

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2004年論文

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2004年論文

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2004年論文

@zh-hk

2004年論文

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2004年論文

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2004年论文

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name

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@ast

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@en

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

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type

label

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@ast

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@en

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@nl

prefLabel

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@ast

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@en

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

@en

P2093

Chuxia Deng

http://www.w3.org/2001/XMLSchema#string

Hiroshi Katayama

http://www.w3.org/2001/XMLSchema#string

Kaori Sasai

http://www.w3.org/2001/XMLSchema#string

Mutsuko Ouchi

http://www.w3.org/2001/XMLSchema#string

Nobuko Fujiuchi

http://www.w3.org/2001/XMLSchema#string

Pat P Ongusaha

http://www.w3.org/2001/XMLSchema#string

Sam W Lee

http://www.w3.org/2001/XMLSchema#string

Subrata Sen

http://www.w3.org/2001/XMLSchema#string

Toru Ouchi

http://www.w3.org/2001/XMLSchema#string

Yohji A Minamishima

http://www.w3.org/2001/XMLSchema#string

P2860

BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

BRCA1-induced large-scale chromatin unfolding and allele-specific effects of cancer-predisposing mutations.

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.

BRCA1 mediates ligand-independent transcriptional repression of the estrogen receptor

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes

BRCA1 regulates p53-dependent gene expression

P304

19643-8

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scholarly article

P3181

1452170

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P356

10.1074/JBC.M311780200

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P407

P433

19

http://www.w3.org/2001/XMLSchema#string

P478

279

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P577

2004-05-07T00:00:00Z

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P698

14990569

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P921

phosphorylation