The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding - Wikidata - awgldk - TriplyDB

The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

http://www.wikidata.org/entity/Q28217015

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SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1 Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells Furin at the cutting edge: from protein traffic to embryogenesis and disease Analysis of Gga null mice demonstrates a non-redundant role for mammalian GGA2 during development Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease Mannose 6-phosphate receptors: new twists in the tale The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Functional organization of the sortilin Vps10p domain.SorCS3 does not require propeptide cleavage to bind nerve growth factor.Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2 Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing.A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes.Bacterial expression, purification, and model membrane reconstitution of the transmembrane and cytoplasmic domains of the human APP binding protein LR11/SorLA for NMR studies.Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.Discovery of short linear motif-mediated interactions through phage display of intrinsically disordered regions of the human proteome.LDLR-related protein 10 (LRP10) regulates amyloid precursor protein (APP) trafficking and processing: evidence for a role in Alzheimer's disease.GGA3 Interacts with a G Protein-Coupled Receptor and Modulates Its Cell Surface Export.A role for cargo in Arf-dependent adaptor recruitment Yeast Golgi-localized, gamma-Ear-containing, ADP-ribosylation factor-binding proteins are but adaptor protein-1 is not required for cell-free transport of membrane proteins from the trans-Golgi network to the prevacuolar compartment.Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention.LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease.Reduction of SorLA/LR11, a sorting protein limiting beta-amyloid production, in Alzheimer disease cerebrospinal fluid.Regulation of α2B-Adrenergic Receptor Cell Surface Transport by GGA1 and GGA2 Toward a model for Arf GTPases as regulators of traffic at the Golgi.Sortilin and SorLA regulate neuronal sorting of trophic and dementia-linked proteins.N-linked oligosaccharides on the low density lipoprotein receptor homolog SorLA/LR11 are modified with terminal GalNAc-4-SO4 in kidney and brain.The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion.RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch.Sorting receptor SORLA: cellular mechanisms and implications for disease.Functional Roles of the Interaction of APP and Lipoprotein Receptors.Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.Cytokine-Like Factor 1, an Essential Facilitator of Cardiotrophin-Like Cytokine:Ciliary Neurotrophic Factor Receptor α Signaling and sorLA-Mediated Turnover.Two motifs target Batten disease protein CLN3 to lysosomes in transfected nonneuronal and neuronal cells.

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The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding

http://www.wikidata.org/entity/Q28217015

description

2002 nî lūn-bûn

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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

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name

The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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prefLabel

The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

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S0014-5793(01)03299-9

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The sorLA cytoplasmic domain i ...... m requirements for GGA binding

@en

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August B Smit

http://www.w3.org/2001/XMLSchema#string

Claus M Petersen

http://www.w3.org/2001/XMLSchema#string

Jørgen Gliemann

http://www.w3.org/2001/XMLSchema#string

Linda Jacobsen

http://www.w3.org/2001/XMLSchema#string

Morten S Nielsen

http://www.w3.org/2001/XMLSchema#string

Peder Madsen

http://www.w3.org/2001/XMLSchema#string

Wijnand P M Geraerts

http://www.w3.org/2001/XMLSchema#string

P2860

A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains

Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding.

A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome

GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex

The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene.

Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin

Vear, a novel Golgi-associated protein with VHS and gamma-adaptin "ear" domains

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155-8

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scholarly article

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3487671

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10.1016/S0014-5793(01)03299-9

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1-3

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511

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2002-01-30T00:00:00Z

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11821067

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