Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA. - Wikidata - awgldk - TriplyDB

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

http://www.wikidata.org/entity/Q40103486

about

Recruitment of the endosomal WASH complex is mediated by the extended 'tail' of Fam21 binding to the retromer protein Vps35 The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production SORLA-dependent and -independent functions for PACS1 in control of amyloidogenic processes GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation Retromer Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families Forty Years of Clathrin-coated Vesicles The retromer complex - endosomal protein recycling and beyond Risk factor SORL1: from genetic association to functional validation in Alzheimer's disease Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11 Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis SorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's disease In situ structural characterization of a recombinant protein in native Escherichia coli membranes with solid-state magic-angle-spinning NMR.Identification of acidic dileucine signals in LRP9 that interact with both GGAs and AP-1/AP-2 Retromer regulates HIV-1 envelope glycoprotein trafficking and incorporation into virions.A membrane proximal helix in the cytosolic domain of the human APP interacting protein LR11/SorLA deforms liposomes.The genetic variation of SORCS1 is associated with late-onset Alzheimer's disease in Chinese Han population.The intracellular domain of sortilin interacts with amyloid precursor protein and regulates its lysosomal and lipid raft trafficking Bacterial expression, purification, and model membrane reconstitution of the transmembrane and cytoplasmic domains of the human APP binding protein LR11/SorLA for NMR studies.BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin.At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis.Rab9-dependent retrograde transport and endosomal sorting of the endopeptidase furin.Physiology and pathology of endosome-to-Golgi retrograde sorting.Schisandrin B protects PC12 cells by decreasing the expression of amyloid precursor protein and vacuolar protein sorting 35.RAB-6.2 and the retromer regulate glutamate receptor recycling through a retrograde pathway.Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex.Sorting protein-related receptor SorLA controls regulated secretion of glial cell line-derived neurotrophic factor.T47D Cells Expressing Myeloperoxidase Are Able to Process, Traffic and Store the Mature Protein in Lysosomes: Studies in T47D Cells Reveal a Role for Cys319 in MPO Biosynthesis that Precedes Its Known Role in Inter-Molecular Disulfide Bond Formation VPS35 Deficiency or Mutation Causes Dopaminergic Neuronal Loss by Impairing Mitochondrial Fusion and Function.New wrinkles in lipoprotein lipase biology.Identification of Alzheimer disease-associated variants in genes that regulate retromer function Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.The role of intracellular trafficking and the VPS10d receptors in Alzheimer's disease.Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1 Drosophila GGA model: an ultimate gateway to GGA analysis.GGA3 Interacts with a G Protein-Coupled Receptor and Modulates Its Cell Surface Export.Screening for VPS35 mutations in Parkinson's disease.

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Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA.

http://www.wikidata.org/entity/Q40103486

description

2007 nî lūn-bûn

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2007年の論文

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年学术文章

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2007年學術文章

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2007年學術文章

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2007年學術文章

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name

Sorting by the cytoplasmic dom ...... rotein binding receptor SorLA.

@en

type

label

Sorting by the cytoplasmic dom ...... rotein binding receptor SorLA.

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prefLabel

Sorting by the cytoplasmic dom ...... rotein binding receptor SorLA.

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Molecular and Cellular Biology

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Sorting by the cytoplasmic dom ...... rotein binding receptor SorLA.

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P2093

André Dennes

http://www.w3.org/2001/XMLSchema#string

Camilla Gustafsen

http://www.w3.org/2001/XMLSchema#string

Claus M Petersen

http://www.w3.org/2001/XMLSchema#string

Guido Hermey

http://www.w3.org/2001/XMLSchema#string

Jens R Nyengaard

http://www.w3.org/2001/XMLSchema#string

Morten S Nielsen

http://www.w3.org/2001/XMLSchema#string

Muriel Mari

http://www.w3.org/2001/XMLSchema#string

Peder Madsen

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Peter Schu

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Regina Pohlmann

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P2860

Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes

The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein

Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme

A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking

LR11, an LDL receptor gene family member, is a novel regulator of smooth muscle cell migration

Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides

Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.

Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer

Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor

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6842-6851

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scholarly article

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10.1128/MCB.00815-07

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19

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27

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17646382

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2099242

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