Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation
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Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1Molecular determinants of substrate selectivity of a novel organic cation transporter (PMAT) in the SLC29 familyIdentification of RNA-protein interaction networks using PAR-CLIPReduced Ribavirin Antiviral Efficacy via Nucleoside Transporter-Mediated Drug ResistanceFUN26 (function unknown now 26) protein from saccharomyces cerevisiae is a broad selectivity, high affinity, nucleoside and nucleobase transporter.Nucleoside transporter subtype expression and function in rat skeletal muscle microvascular endothelial cellsEquilibrative nucleoside transporters-A review.Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2).Tyrosine 112 is essential for organic cation transport by the plasma membrane monoamine transporterNucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.Regulation of equilibrative nucleoside uptake by protein kinase inhibitors.Residue Ile89 in human plasma membrane monoamine transporter influences its organic cation transport activity and sensitivity to inhibition by dilazepReduced adenosine release from the aged mammalian heartPurine and pyrimidine transport in pathogenic protozoa: from biology to therapy.Cysteine cross-linking defines the extracellular gate for the Leishmania donovani nucleoside transporter 1.1 (LdNT1.1).Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals.Renal nucleoside transporters: physiological and clinical implications.Concentrative nucleoside transporters (CNTs) in epithelia: from absorption to cell signaling.The role of mitochondrial and plasma membrane nucleoside transporters in drug toxicity.An ab Initio structural model of a nucleoside permease predicts functionally important residues.Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F).Dipyridamole analogs as pharmacological inhibitors of equilibrative nucleoside transporters. Identification of novel potent and selective inhibitors of the adenosine transporter function of human equilibrative nucleoside transporter 4 (hENT4).Human nucleoside transporters: biomarkers for response to nucleoside drugs.Functional characterization of human equilibrative nucleoside transporter 1.Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition.Nucleoside/nucleobase transporters: drug targets of the future?Translocation of nucleoside analogs across the plasma membrane in hematologic malignancies.D-Glucose upregulates adenosine transport in cultured human aortic smooth muscle cells.Equilibrative Nucleoside Transporters 1 and 4: Which One Is a Better Target for Cardioprotection Against Ischemia-Reperfusion Injury?The Adenosinergic System as a Therapeutic Target in the Vasculature: New Ligands and Challenges.Role of Equilibrative Nucleobase Transporter 1/SLC43A3 as a Ganciclovir Transporter in the Induction of Cytotoxic Effect of Ganciclovir in a Suicide Gene Therapy with Herpes Simplex Virus Thymidine Kinase.Comparative in vitro evaluation of transportability and toxicity of capecitabine and its metabolites in cells derived from normal human kidney and renal cancers.ENT1, a ribavirin transporter, plays a pivotal role in antiviral efficacy of ribavirin in a hepatitis C virus replication cell system.Identification and functional characterization of the first nucleobase transporter in mammals: implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammalsSubstituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importanceExpression and functional activity of nucleoside transporters in human choroid plexus.Hypoxanthine decreases equilibrative type of adenosine transport in lymphocytes from Lesch-Nyhan patients.Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3.AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis.
P2860
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P2860
Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation
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2002 nî lūn-bûn
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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Functional and molecular chara ...... on in nucleobase translocation
@ast
Functional and molecular chara ...... on in nucleobase translocation
@en
Functional and molecular chara ...... on in nucleobase translocation
@nl
type
label
Functional and molecular chara ...... on in nucleobase translocation
@ast
Functional and molecular chara ...... on in nucleobase translocation
@en
Functional and molecular chara ...... on in nucleobase translocation
@nl
prefLabel
Functional and molecular chara ...... on in nucleobase translocation
@ast
Functional and molecular chara ...... on in nucleobase translocation
@en
Functional and molecular chara ...... on in nucleobase translocation
@nl
P2093
P2860
P356
P1476
Functional and molecular chara ...... on in nucleobase translocation
@en
P2093
Amy M L Ng
Carol E Cass
James D Young
Manickavasagam Sundaram
Mark F Vickers
Sylvia Y M Yao
P2860
P304
P356
10.1074/JBC.M200966200
P407
P577
2002-07-12T00:00:00Z