Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy. - Wikidata - awgldk - TriplyDB

Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.

Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.

http://www.wikidata.org/entity/Q35567292

about

Polyplex Nanogel formulations for drug delivery of cytotoxic nucleoside analogs.Marine nucleosides: structure, bioactivity, synthesis and biosynthesis Reduced Ribavirin Antiviral Efficacy via Nucleoside Transporter-Mediated Drug Resistance Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters Update on the management of pancreatic cancer: surgery is not enough Characterization of the rat Na+/nucleoside cotransporter 2 and transport of nucleoside-derived drugs using electrophysiological methods Equilibrative nucleoside transporters-A review.Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity.A novel in vitro assay to assess phosphorylation of 3'-[(18)F]fluoro-3'-deoxythymidine.Cellular influx, efflux, and anabolism of 3-carboranyl thymidine analogs: potential boron delivery agents for neutron capture therapy Equilibrative nucleoside transporter 1 genotype, cytidine deaminase activity and age predict gemcitabine plasma clearance in patients with solid tumours.Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3.Efficient microwave-assisted solid phase coupling of nucleosides, small library generation and mild conditions for release of nucleoside derivatives Clinical pharmacology and pharmacogenetics of gemcitabine.Prognostic value of human equilibrative nucleoside transporter1 in pancreatic cancer receiving gemcitabin-based chemotherapy: a meta-analysis.Pharmacodynamics of cytarabine induced leucopenia: a retrospective cohort study Novel strategy with gemcitabine for advanced pancreatic cancer.Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1.A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3 Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles.Different modes of transport for 3H-thymidine, 3H-FLT, and 3H-FMAU in proliferating and nonproliferating human tumor cells.Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML Stratification of nucleoside analog chemotherapy using 1-(2'-deoxy-2'-18F-fluoro-β-D-arabinofuranosyl)cytosine and 1-(2'-deoxy-2'-18F-fluoro-β-L-arabinofuranosyl)-5-methylcytosine PET.Application of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells.Synthesis and anti-HIV activities of bis-(cycloSaligenyl) pronucleotides derivatives of 3'-fluoro-3'-deoxythymidine and 3'-azido-3'-deoxythymidine.Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-Fluorouracil-Mediated Cytotoxicity in Multiple Human Cancer Types.Mechanisms and insights into drug resistance in cancer Renal nucleoside transporters: physiological and clinical implications.Ex vivo chemosensitivity testing and gene expression profiling predict response towards adjuvant gemcitabine treatment in pancreatic cancer Overcoming S-phase checkpoint-mediated resistance: sequence-dependent synergy of gemcitabine and 7-ethyl-10-hydroxycamptothecin (SN-38) in human carcinoma cell lines Physiology of nucleoside transporters: back to the future. . . .Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3 Antifreeze protein-induced selective crystallization of a new thermodynamically and kinetically less preferred molecular crystal.The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family.Human nucleoside transporters: biomarkers for response to nucleoside drugs.Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2.Fluorinase: a tool for the synthesis of ¹⁸F-labeled sugars and nucleosides for PET.Translocation of nucleoside analogs across the plasma membrane in hematologic malignancies.Emerging transporters of clinical importance: an update from the International Transporter Consortium.

P2860

Q24540353-051164A9-42E7-42C7-B3F4-0055D198478C Q26995473-F3E312F9-C69B-4522-96CF-94819587369D Q27488307-3DF765CA-485A-4860-BD2A-63872FE0CAEB Q27677998-FAE7630F-6E7B-47ED-BE6C-47CED9A54EB7 Q27684896-B3992D7D-2900-403C-847E-02708C94ECE7 Q28087060-0386F1ED-3CAD-4F35-8B05-DCF82DC4D566 Q28564201-60DF4B10-9ACD-4A7B-BE4E-2CA0E62A518C Q30244329-7C89B5C0-4AA6-4D33-ACCC-7273662BFCE8 Q34159634-C5CF0ABD-1B93-4C62-882C-B22368EC9180 Q34267713-2D3A89A2-8495-4356-B0C5-EC0B2160A962 Q34368734-7277E5C0-E277-4225-82EC-29C799909DBE Q34609029-098D9E41-F65B-4356-A947-A2FAA445C3C3 Q34622000-AB075A2D-3E51-4E3A-AEF1-5C8012E05FAE Q34781847-7F84513C-A23A-4341-ADAE-C4D5153E10AE Q34985979-745D947E-23FB-4D05-A2E1-1F034F5A96BE Q35086475-AF7B0650-9EA0-4F7B-B7CF-C3274A9BC838 Q35286194-1CBC44FF-3480-446D-8495-A75221648536 Q35432223-D5A7833D-43A0-41C7-A1A3-09FBAF8FAA44 Q35610203-456A5C7D-2888-4AB0-94A3-F642A57E3CCC Q35676740-A5F8DA53-5608-42B9-8398-DCCFE61289CE Q35909171-0523D32A-1CE7-43C9-9C4C-D3252571B82E Q36012091-24C49181-51B0-4038-B77E-871094820700 Q36180934-5460B653-8B4A-4568-A756-019854492AE3 Q36201693-E37207FA-6DE5-4549-A840-594FDAE0A72D Q36291296-91B9DBA0-D9EA-418C-83DE-28F33A34E3B8 Q36362416-E773C9A3-40D2-4A97-86D0-DDE13814732C Q36602123-ABFEDFD3-C86C-4427-8F6A-06B84089F7B5 Q36682301-EC9B2851-D488-4D15-8E8B-4809C06EAC76 Q36704491-BD624505-9EC9-4FD5-A142-00953A38418C Q36859193-C6653A45-7095-4995-A965-99F1F7B920EE Q36952729-9CD0D7C6-CFD8-49C0-B482-0B1F21CF9746 Q37082372-AE0FDE7C-4646-4291-928F-C452DBC3187B Q37285168-87368538-18C5-4906-9C31-E11ECC9EC746 Q37374940-D525260C-9341-4B22-A547-C1834940F151 Q37605606-6BD2DB63-ADD4-46ED-A2D2-978925E2B6FA Q37698437-F2522EE3-40C7-42F4-B74C-F54AA84D906A Q37713632-EA859CB3-28E1-448C-9ECF-92A0002FD48C Q37855878-985C5F39-D7AB-410F-8B46-11672D9ED1B1 Q37963498-CEF43D18-B55C-48CE-B4DA-54FEC580EDDA Q38099192-F13E6EDE-C687-4843-9F88-CDFA5FD5163C

P2860

Nucleoside anticancer drugs: the role of nucleoside transporters in resistance to cancer chemotherapy.

http://www.wikidata.org/entity/Q35567292

description

2003 nî lūn-bûn

@nan

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

2003年论文

@zh

2003年论文

@zh-cn

name

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@ast

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@en

type

label

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@ast

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@en

prefLabel

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@ast

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@en

P1433

Q35567292-378759C1-1866-4380-960F-3229CFAD4746

P1476

Q35567292-BEBA8DB9-5280-49FB-8497-E05D2F9AABB4

P2093

Q35567292-012D87BA-52CE-4A85-A35A-6E5BE83F871D

Q35567292-4A9B5199-CD74-44C9-A103-F049C19AB074

Q35567292-87E7AF6E-5D08-4F79-9533-C1F30DDF3CAD

Q35567292-C8E34AA2-B372-451C-AAD1-37FE79BB44EC

Q35567292-CB2810E8-0078-4548-990C-AC10A56F5E5E

Q35567292-F2751325-5027-424F-88A0-35699B5F5C51

P2860

Q35567292-03B67E13-309D-4098-AC7B-C2787F4646B7

Q35567292-03D0CA74-F611-4F2B-AC19-5A0F05377D8E

Q35567292-03DEDAAD-5D52-46AC-AE94-7D3E190BE777

Q35567292-06AB8BC8-7D35-4963-B140-7BB36F7FA61F

Q35567292-06DA8535-4795-4A1E-8DE6-247F4197F9AD

Q35567292-0D3E98F9-DC51-4486-8957-35703DD2273E

Q35567292-0F537DFD-14A0-4AF5-BC34-6D3450121ED8

Q35567292-1E35C61C-C803-4861-A385-7A92FF729D05

Q35567292-2BBA8931-FFE0-429E-9F6E-01EA07DE68D8

Q35567292-2E4CDF8F-0B88-4A46-9EAB-71BA9EA31109

P2888

Q35567292-9F4E635D-0B75-4E66-A099-01A1B475F92B

P304

Q35567292-82072B82-4CF5-4882-BF00-0E31F4B32934

P31

Q35567292-67BE199A-4578-4C63-907D-C0DCD8A13B85

P356

Q35567292-C98CCEDE-CBB5-43F0-AFD4-34238ED662F2

P407

Q35567292-FD0A8B7F-EBD7-4A35-9556-ACFF38D2F4C7

P433

Q35567292-8F89829B-1FF6-40D7-B7A7-2CE688A08C40

P478

Q35567292-B0807318-3A7E-43DE-A6B9-D64FAE03D575

P50

Q35567292-E86AEBEE-31B1-40A0-BD3A-D79C4639FF8E

P577

Q35567292-0E5282E5-8FB8-4C05-9733-0018B393851E

P698

Q35567292-86D95588-227F-409C-A59E-4714399CFE6B

P921

Q35567292-5DC54C3A-570F-4F97-9036-BA66A1AB7804

P356

P1433

P1476

Nucleoside anticancer drugs: t ...... stance to cancer chemotherapy.

@en

P2093

Carol E Cass

http://www.w3.org/2001/XMLSchema#string

James D Young

http://www.w3.org/2001/XMLSchema#string

John Mackey

http://www.w3.org/2001/XMLSchema#string

Michael B Sawyer

http://www.w3.org/2001/XMLSchema#string

Sambasivarao Damaraju

http://www.w3.org/2001/XMLSchema#string

Vijaya L Damaraju

http://www.w3.org/2001/XMLSchema#string

P2860

Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs

Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta

Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity.

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

Characterization of single-nucleotide polymorphisms in coding regions of human genes

Gemcitabine and cisplatin versus methotrexate, vinblastine, doxorubicin, and cisplatin in advanced or metastatic bladder cancer: results of a large, randomized, multinational, multicenter, phase III study

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

Functional and molecular characterization of nucleobase transport by recombinant human and rat equilibrative nucleoside transporters 1 and 2. Chimeric constructs reveal a role for the ENT2 helix 5-6 region in nucleobase translocation

Cloning of the human equilibrative, nitrobenzylmercaptopurine riboside (NBMPR)-insensitive nucleoside transporter ei by functional expression in a transport-deficient cell line

A phase I clinical, plasma, and cellular pharmacology study of gemcitabine

P2888

P304

7524-7536

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1206952

http://www.w3.org/2001/XMLSchema#string

P407

P433

47

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P50

Stephen A. Baldwin

P577

2003-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

14576856

http://www.w3.org/2001/XMLSchema#string

P921