Intracellular activation of human adamalysin 19/disintegrin and metalloproteinase 19 by furin occurs via one of the two consecutive recognition sites
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Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi networkCatalytic properties of ADAM19Activation of pro-gelatinase B by endometase/matrilysin-2 promotes invasion of human prostate cancer cellsAutolytic processing at Glu586-Ser587 within the cysteine-rich domain of human adamalysin 19/disintegrin-metalloproteinase 19 is necessary for its proteolytic activityEssential role for ADAM19 in cardiovascular morphogenesisThe study of the inhibition of the recombinant TACE prodomain to endotoxemia in mice.ADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesis.Metalloproteinase dependent reduction of cell surface cluster determinants upon the induction of apoptosis.The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site.Application of structural dynamic approaches provide novel insights into the enzymatic mechanism of the tumor necrosis factor-alpha-converting enzymeProprotein convertases play an important role in regulating PKGI endoproteolytic cleavage and nuclear transport.Formation of Pmel17 amyloid is regulated by juxtamembrane metalloproteinase cleavage, and the resulting C-terminal fragment is a substrate for gamma-secretaseADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.ADAM-15 disintegrin-like domain structure and function.Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its effects on cell invasion and adhesion in human trophoblastic cells.TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity.Chaperone-like properties of the prodomain of TNFalpha-converting enzyme (TACE) and the functional role of its cysteine switch.Regional expression of ADAM19 during chicken embryonic development.Inhibition of the tumor necrosis factor-alpha-converting enzyme by its pro domain.Identification of prodomain determinants involved in ADAMTS-1 biosynthesis.High expression of the "A Disintegrin And Metalloprotease" 19 (ADAM19), a sheddase for TNF-α in the mucosa of patients with inflammatory bowel diseases.Overexpression of TNF-α-converting enzyme in fibroblasts augments dermal fibrosis after inflammation.
P2860
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P2860
Intracellular activation of human adamalysin 19/disintegrin and metalloproteinase 19 by furin occurs via one of the two consecutive recognition sites
description
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im Juli 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 12 July 2002)
@en
vedecký článok (publikovaný 2002/07/12)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/07/12)
@nl
наукова стаття, опублікована в липні 2002
@uk
name
Intracellular activation of hu ...... consecutive recognition sites
@ast
Intracellular activation of hu ...... consecutive recognition sites
@en
Intracellular activation of hu ...... consecutive recognition sites
@nl
type
label
Intracellular activation of hu ...... consecutive recognition sites
@ast
Intracellular activation of hu ...... consecutive recognition sites
@en
Intracellular activation of hu ...... consecutive recognition sites
@nl
prefLabel
Intracellular activation of hu ...... consecutive recognition sites
@ast
Intracellular activation of hu ...... consecutive recognition sites
@en
Intracellular activation of hu ...... consecutive recognition sites
@nl
P2093
P356
P1476
Intracellular activation of hu ...... consecutive recognition sites
@en
P2093
Duanqing Pei
Joseph F Sucic
Qing-Xiang Amy Sang
Tiebang Kang
Yun-Ge Zhao
P304
P356
10.1074/JBC.M203532200
P407
P577
2002-07-12T00:00:00Z