Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
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PharmGKB summary: very important pharmacogene information for UGT1A1Dimerization of human uridine diphosphate glucuronosyltransferase allozymes 1A1 and 1A9 alters their quercetin glucuronidation activitiesDrug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical simulation.Nanocrystals of a new camptothecin derivative WCN-21 enhance its solubility and efficacyReduced total serum bilirubin levels are associated with ulcerative colitisA humanized UGT1 mouse model expressing the UGT1A1*28 allele for assessing drug clearance by UGT1A1-dependent glucuronidationThe human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation.Mapping of the UGT1A locus identifies an uncommon coding variant that affects mRNA expression and protects from bladder cancer.Pharmacogenomics of drug metabolizing enzymes and transporters: implications for cancer therapy.Phytochemical regulation of UDP-glucuronosyltransferases: implications for cancer prevention.Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell linesPharmacogenetics of Gilbert's syndrome.UGT1A1 gene polymorphism: impact on toxicity and efficacy of irinotecan-based regimens in metastatic colorectal cancer.Gene replacement therapy for genetic hepatocellular jaundice.Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer.Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases.Association between UGT1A1*28*28 genotype and lung cancer in the Japanese population.Gilbert-Meulengracht's syndrome and pharmacogenetics: is jaundice just the tip of the iceberg?UGT1A1, UGT1A6 and UGT1A7 genetic analysis: repercussion for irinotecan pharmacogenetics in the São Miguel Island Population (Azores, Portugal).Disruption of the ugt1 locus in mice resembles human Crigler-Najjar type I disease.Influence of genetic variants in UGT1A1 and UGT1A9 on the in vivo glucuronidation of SN-38.Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.
P2860
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P2860
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
description
2002 nî lūn-bûn
@nan
2002 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@ast
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@en
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@nl
type
label
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@ast
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@en
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@nl
prefLabel
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@ast
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@en
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@nl
P2093
P3181
P356
P1476
Pharmacogenomics of human UDP-glucuronosyltransferases and irinotecan toxicity
@en
P2093
Christian P Strassburg
Peter I Mackenzie
Robert H Tukey
P304
P3181
P356
10.1124/MOL.62.3.446
P407
P577
2002-09-01T00:00:00Z