Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
about
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The WASP and WAVE family proteinsRac and Rho GTPases in cancer cell motility controlInclusion of Scar/WAVE3 in a similar complex to Scar/WAVE1 and 2CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formationEPLIN regulates actin dynamics by cross-linking and stabilizing filamentsAnalysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturationWASH and the Arp2/3 complex regulate endosome shape and trafficking.Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxisUbiquitylation-dependent downregulation of Nck regulates its functional activityProtein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexinStructure and control of the actin regulatory WAVE complexWHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transportNESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylationWASH and WAVE actin regulators of the Wiskott-Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexesPLC-gamma1 and Rac1 coregulate EGF-induced cytoskeleton remodeling and cell migrationRegulation of WASH-dependent actin polymerization and protein trafficking by ubiquitinationLocal F-actin network links synapse formation and axon branchingKank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1Free Brick1 is a trimeric precursor in the assembly of a functional wave complexThe Cdc42 effector IRSp53 generates filopodia by coupling membrane protrusion with actin dynamicsNYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neuronsCortactin signalling and dynamic actin networksLoss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.WASP family proteins: their evolution and its physiological implications.Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsThe yeast actin cytoskeleton: from cellular function to biochemical mechanismBcr-Abl induces abnormal cytoskeleton remodeling, beta1 integrin clustering and increased cell adhesion to fibronectin through the Abl interactor 1 pathwayThe murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin networkGTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivoRapid de-localization of actin leading edge components with BDM treatmentDissecting Nck/Dock signaling pathways in Drosophila visual system.Unravelling the Actin Cytoskeleton: A New Competitive Edge?Regulators of Actin Dynamics in Gastrointestinal Tract TumorsPhysical view on migration modesPhosphoregulation of the WAVE regulatory complex and signal integrationFunctions and regulation of circular dorsal rufflesUnder lock and key: spatiotemporal regulation of WASP family proteins coordinates separate dynamic cellular processesThe FMRP regulon: from targets to disease convergenceAlzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss.Rab1 recruits WHAMM during membrane remodeling but limits actin nucleation.
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P2860
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@ast
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@en
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@nl
type
label
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@ast
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@en
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@nl
prefLabel
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@ast
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@en
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@nl
P2093
P2860
P3181
P356
P1433
P1476
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
@en
P2093
Alexandre V Podtelejnikov
Marc W Kirschner
Matthias Mann
Rajat Rohatgi
Sharon Eden
P2860
P2888
P3181
P356
10.1038/NATURE00859
P407
P577
2002-08-15T00:00:00Z
P6179
1035769834