An alternative flavin-dependent mechanism for thymidylate synthesis
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Swine and poultry pathogens: the complete genome sequences of two strains of Mycoplasma hyopneumoniae and a strain of Mycoplasma synoviaeGenome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genomeComplete genome sequence of the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1 and comparison with Pyrococcus genomesThe genome of the social amoeba Dictyostelium discoideumSulfolobus tengchongensis spindle-shaped virus STSV1: virus-host interactions and genomic features.Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.Three RNA cells for ribosomal lineages and three DNA viruses to replicate their genomes: a hypothesis for the origin of cellular domainThe Phycodnaviridae: the story of how tiny giants rule the worldEnigmatic, ultrasmall, uncultivated Archaea.Comparative genomics of Archaea: how much have we learned in six years, and what's next?Detection of evolutionarily stable fragments of cellular pathways by hierarchical clustering of phyletic patternsA comprehensive evolutionary classification of proteins encoded in complete eukaryotic genomesIdentification of a novel gene encoding a flavin-dependent tRNA:m5U methyltransferase in bacteria--evolutionary implicationsFlavin-Dependent Thymidylate Synthase as a New Antibiotic TargetAn unusual mechanism of thymidylate biosynthesis in organisms containing the thyX geneAtomic structure of a folate/FAD-dependent tRNA T54 methyltransferase.Folate binding site of flavin-dependent thymidylate synthaseMechanistic and structural basis for inhibition of thymidylate synthase ThyXFlavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor DesignMycobacterium tuberculosis folate metabolism and the mechanistic basis for para-aminosalicylic acid susceptibility and resistanceKinetics and ligand-binding preferences of Mycobacterium tuberculosis thymidylate synthases, ThyA and ThyXThe case for an early biological origin of DNAThe origin of modern terrestrial lifeAnalysis of genomic context: prediction of functional associations from conserved bidirectionally transcribed gene pairsStructural analysis of polarizing indels: an emerging consensus on the root of the tree of lifeFunctional analysis of the Mycobacterium tuberculosis FAD-dependent thymidylate synthase, ThyX, reveals new amino acid residues contributing to an extended ThyX motif.Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue.Evolution of eukaryotic gene repertoire and gene structure: discovering the unexpected dynamics of genome evolution.'Conserved hypothetical' proteins: prioritization of targets for experimental studyFunctional evidence for active site location of tetrameric thymidylate synthase X at the interphase of three monomers.Catalytic mechanism of Chlamydia trachomatis flavin-dependent thymidylate synthase.Archaeal Pyrococcus furiosus thymidylate synthase 1 is an RNA-binding proteinComparative genomics of bacterial and plant folate synthesis and salvage: predictions and validationsSubstrate activation in flavin-dependent thymidylate synthase.Phylogenetic evidence for extensive lateral acquisition of cellular genes by Nucleocytoplasmic large DNA virusesEvolutionary constraints permeate large metabolic networksAn evolutionary analysis of lateral gene transfer in thymidylate synthase enzymes.Crystallization and preliminary crystallographic studies of a flavin-dependent thymidylate synthase from Helicobacter pylori.Chlorella virus-encoded deoxyuridine triphosphatases exhibit different temperature optima.When the Web meets the cell: using personalized PageRank for analyzing protein interaction networks.
P2860
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P2860
An alternative flavin-dependent mechanism for thymidylate synthesis
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
An alternative flavin-dependent mechanism for thymidylate synthesis
@ast
An alternative flavin-dependent mechanism for thymidylate synthesis
@en
An alternative flavin-dependent mechanism for thymidylate synthesis
@nl
type
label
An alternative flavin-dependent mechanism for thymidylate synthesis
@ast
An alternative flavin-dependent mechanism for thymidylate synthesis
@en
An alternative flavin-dependent mechanism for thymidylate synthesis
@nl
prefLabel
An alternative flavin-dependent mechanism for thymidylate synthesis
@ast
An alternative flavin-dependent mechanism for thymidylate synthesis
@en
An alternative flavin-dependent mechanism for thymidylate synthesis
@nl
P2093
P3181
P356
P1433
P1476
An alternative flavin-dependent mechanism for thymidylate synthesis
@en
P2093
Damien Leduc
Gerard Lipowski
Hannu Myllykallio
Jonathan Filee
Ursula Liebl
P3181
P356
10.1126/SCIENCE.1072113
P407
P577
2002-07-05T00:00:00Z