Folate binding site of flavin-dependent thymidylate synthase - Wikidata - awgldk - TriplyDB

Folate binding site of flavin-dependent thymidylate synthase

Folate binding site of flavin-dependent thymidylate synthase

http://www.wikidata.org/entity/Q27673716

about

Flavin-Dependent Thymidylate Synthase as a New Antibiotic Target Clinical significance of ERCC1, RRM1 and TS in non-small cell lung cancer Mechanistic and structural basis for inhibition of thymidylate synthase ThyX Flavin-Dependent Thymidylate Synthase as a Drug Target for Deadly Microbes: Mutational Study and a Strategy for Inhibitor Design Deprotonations in the Reaction of Flavin-Dependent Thymidylate Synthase Discovery of an acyclic nucleoside phosphonate that inhibits Mycobacterium tuberculosis ThyX based on the binding mode of a 5-alkynyl substrate analogue.Substrate activation in flavin-dependent thymidylate synthase.Ultrafast real-time visualization of active site flexibility of flavoenzyme thymidylate synthase ThyX An unprecedented mechanism of nucleotide methylation in organisms containing thyX.From chemical metabolism to life: the origin of the genetic coding process.Detection of intermediates in the oxidative half-reaction of the FAD-dependent thymidylate synthase from Thermotoga maritima: carbon transfer without covalent pyrimidine activation.Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier.Unique Features and Anti-microbial Targeting of Folate- and Flavin-Dependent Methyltransferases Required for Accurate Maintenance of Genetic Information.

P2860

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P2860

Folate binding site of flavin-dependent thymidylate synthase

http://www.wikidata.org/entity/Q27673716

description

2012 nî lūn-bûn

@nan

2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

Folate binding site of flavin-dependent thymidylate synthase

@ast

Folate binding site of flavin-dependent thymidylate synthase

@en

Folate binding site of flavin-dependent thymidylate synthase

@nl

type

label

Folate binding site of flavin-dependent thymidylate synthase

@ast

Folate binding site of flavin-dependent thymidylate synthase

@en

Folate binding site of flavin-dependent thymidylate synthase

@nl

prefLabel

Folate binding site of flavin-dependent thymidylate synthase

@ast

Folate binding site of flavin-dependent thymidylate synthase

@en

Folate binding site of flavin-dependent thymidylate synthase

@nl

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PNAS.1206077109

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Folate binding site of flavin-dependent thymidylate synthase

@en

P2093

Amnon Kohen

http://www.w3.org/2001/XMLSchema#string

Arjun Prabhakar

http://www.w3.org/2001/XMLSchema#string

Eric M Koehn

http://www.w3.org/2001/XMLSchema#string

Irimpan I Mathews

http://www.w3.org/2001/XMLSchema#string

Laura L Perissinotti

http://www.w3.org/2001/XMLSchema#string

Salah Moghram

http://www.w3.org/2001/XMLSchema#string

Scott A Lesley

http://www.w3.org/2001/XMLSchema#string

P2860

Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline.

Catalytic cycle of human glutathione reductase near 1 A resolution

Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug

Functional analysis of substrate and cofactor complex structures of a thymidylate synthase-complementing protein

An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene

Atomic structure of a folate/FAD-dependent tRNA T54 methyltransferase.

Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug

An alternative flavin-dependent mechanism for thymidylate synthesis

The catalytic mechanism and structure of thymidylate synthase

Kinetics and ligand-binding preferences of Mycobacterium tuberculosis thymidylate synthases, ThyA and ThyX

P304

15722-7

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scholarly article

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10.1073/PNAS.1206077109

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39

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109

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2012-09-25T00:00:00Z

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231225487

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23019356

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P932

3465422

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